Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | RARB | P10826 | 3/20 | 0.43 |
| ▸ | BRS3 | P32247 | 2/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MPL | P40238 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9060741 | 0.96 | PPARA (0.47) | HSD11B1PPARARARBPPARGPTPN1 | |
| SCHEMBL9061670 | 0.95 | RARB (0.49) | HSD11B1PPARARARBPTPN1 | |
| SCHEMBL9061533 | 0.95 | RARB (0.49) | HSD11B1PPARARARBPTPN1 | |
| SCHEMBL9062058 | 0.95 | RARB (0.49) | HSD11B1PPARARARBPTPN1 | |
| SCHEMBL9061547 | 0.95 | RARB (0.49) | HSD11B1PPARARARBPTPN1 | |
| SCHEMBL9061026 | 0.95 | RARB (0.49) | HSD11B1PPARARARBPTPN1 | |
| SCHEMBL9061315 | 0.92 | PPARA (0.44) | PPARAPPARGDAGLA | |
| SCHEMBL8377179 | 0.89 | PPARA (0.47) | HSD11B1PPARARARBPSMB5PPARG | |
| SCHEMBL9060997 | 0.88 | PSMB5 (0.45) | PPARAPSMB5PPARG | |
| SCHEMBL9060317 | 0.87 | PPARG (0.46) | PPARAPPARGDAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536442-A | ELECTROOPTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-16 | — | — | US | disclosed |
| US-5389292-A | Liquid crystalline media having positive dielctric anisotropy, chemical, heat and radiation resistance, used as electro-optical displaying | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-14 | — | — | US | disclosed |
| EP-0381728-B1 | DIFLUOROMETHYL COMPOUNDS | MERCK PATENT GMBH (DE) | 1993-12-08 | — | — | EP | disclosed |