Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593785 | 0.87 | NOTUM (0.42) | NOTUMKDM4EPOLBALDH1A1TSHR | |
| SCHEMBL1924917 | 0.81 | NOTUM (0.62) | NOTUMKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL31462133 | 0.75 | PARP1 (0.42) | NOTUMKDM4EPARP1ALDH1A1MAPT | |
| SCHEMBL608411 | 0.75 | NOTUM (0.43) | NOTUMKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL29370778 | 0.75 | NOTUM (0.66) | NOTUMPARP1KMT2ATSHRRAB9A | |
| SCHEMBL3649822 | 0.75 | NOTUM (0.66) | NOTUMPARP1KMT2ATSHRRAB9A | |
| SCHEMBL16339984 | 0.74 | NOTUM (0.45) | NOTUMKDM4EPARP1POLBALDH1A1 | |
| SCHEMBL19810738 | 0.74 | MAPK1 (0.40) | KDM4EPOLBALDH1A1ERCC1FEN1 | |
| SCHEMBL8579432 | 0.74 | MAPK1 (0.40) | KDM4EPOLBALDH1A1ERCC1FEN1 | |
| SCHEMBL6216786 | 0.74 | PARP1 (0.53) | NOTUMKDM4EPARP1FEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8311066-A | — | — | None | — | — | JP | disclosed |
| JP-H08311066-A | NEW 4-OXOQUINOLINECARBOXAMIDE DERIVATIVE OR ITS SALT | YAMANOUCHI PHARMACEUT CO LTD | 1996-11-26 | — | — | JP | disclosed |