Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | PRPS1 | P60891 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ADCY5 | O95622 | 5/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607405 | 0.80 | IDO1 (0.43) | IDO1KCNH2CYP2C9PRPS1THRB | |
| SCHEMBL7607409 | 0.80 | IDO1 (0.43) | IDO1KCNH2CYP2C9PRPS1THRB | |
| SCHEMBL7611525 | 0.80 | IDO1 (0.43) | IDO1KCNH2CYP2C9PRPS1THRB | |
| SCHEMBL8586343 | 0.78 | THRB (0.41) | IDO1KCNH2CYP2C9PRPS1THRB | |
| SCHEMBL8586347 | 0.78 | THRB (0.41) | IDO1KCNH2CYP2C9PRPS1THRB | |
| SCHEMBL9407209 | 0.75 | CCNT1 (0.43) | IRAK4CCNT1CDK9PTGESJAK2 | |
| SCHEMBL9061680 | 0.75 | CCNT1 (0.43) | IRAK4CCNT1CDK9PTGESJAK2 | |
| SCHEMBL9061855 | 0.73 | NR1I2 (0.42) | IDO1KCNH2CYP2C9PRPS1THRB | |
| SCHEMBL7624390 | 0.73 | THRB (0.39) | IDO1KCNH2CYP2C9PRPS1THRB | |
| SCHEMBL6947613 | 0.73 | THRB (0.40) | IDO1KCNH2CYP2C9PRPS1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534535-A | ANTIVIRAL ANALOGS WITH SUBSTITUTED BENZIMIDAZOLE BASE | BURROUGHS WELLCOME CO. (US) | 1996-07-09 | — | — | US | disclosed |
| US-5399580-A | Viricides for hepatitis B | BURROUGHS WELLCOME CO. (US) | 1995-03-21 | — | — | US | disclosed |