Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PRPS1 | P60891 | 6/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | AHCY | P23526 | 2/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8586347 | 1.00 | THRB (0.41) | THRBPRPS1CYP2C9IDO1KCNH2 | |
| SCHEMBL9119445 | 0.80 | AHCY (0.57) | THRBAHCY | |
| SCHEMBL8525973 | 0.80 | AHCY (0.57) | THRBAHCY | |
| SCHEMBL8525972 | 0.80 | AHCY (0.57) | THRBAHCY | |
| SCHEMBL9120372 | 0.80 | AHCY (0.57) | THRBAHCY | |
| SCHEMBL9120465 | 0.80 | AHCY (0.57) | THRBAHCY | |
| SCHEMBL9060965 | 0.78 | IDO1 (0.42) | THRBPRPS1CYP2C9IDO1KCNH2 | |
| SCHEMBL7616161 | 0.77 | PRPS1 (0.48) | THRBPRPS1KCNH2 | |
| SCHEMBL7616155 | 0.77 | PRPS1 (0.48) | THRBPRPS1KCNH2 | |
| SCHEMBL7616152 | 0.77 | PRPS1 (0.48) | THRBPRPS1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912356-A | HERPES VIRUS | GLAXO WELLCOME INC. (US) | 1999-06-15 | — | — | US | disclosed |
| EP-0630368-B1 | ANTIVIRAL NUCLEOSIDE ANALOGUES | WELLCOME FOUND (GB) | 1998-09-09 | — | — | EP | disclosed |
| US-5534535-A | ANTIVIRAL ANALOGS WITH SUBSTITUTED BENZIMIDAZOLE BASE | BURROUGHS WELLCOME CO. (US) | 1996-07-09 | — | — | US | disclosed |