Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 4/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9060761 | 0.96 | PPARA (0.44) | PSMB5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9062068 | 0.95 | PPARA (0.46) | PSMB5BACE1FAAHPTGS2PPARG | |
| SCHEMBL9061676 | 0.95 | PPARA (0.46) | PSMB5BACE1FAAHPTGS2PPARG | |
| SCHEMBL9061538 | 0.95 | PPARA (0.46) | PSMB5BACE1FAAHPTGS2PPARG | |
| SCHEMBL9061034 | 0.95 | PPARA (0.46) | PSMB5BACE1FAAHPTGS2PPARG | |
| SCHEMBL9061554 | 0.95 | PPARA (0.46) | PSMB5BACE1FAAHPTGS2PPARG | |
| SCHEMBL9061321 | 0.93 | PDE4B (0.41) | PSMB5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9060992 | 0.88 | HSD11B1 (0.44) | PSMB5PPARGPPARA | |
| SCHEMBL9060323 | 0.87 | PDE4B (0.43) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL8377179 | 0.86 | PPARA (0.47) | PSMB5BACE1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536442-A | ELECTROOPTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-16 | — | — | US | disclosed |
| US-5389292-A | Liquid crystalline media having positive dielctric anisotropy, chemical, heat and radiation resistance, used as electro-optical displaying | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-14 | — | — | US | disclosed |