Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | PDE9A | O76083 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9060665 | 0.77 | PDE9A (0.41) | PTPN1ALDH1A1HSD17B10ALOX15PDE9A | |
| SCHEMBL2778432 | 0.76 | MAPT (0.57) | ALDH1A1HSD17B10ALOX15KDM4EMAPT | |
| SCHEMBL1902220 | 0.74 | MAPT (0.55) | ALDH1A1HSD17B10ALOX15KDM4EMAPT | |
| SCHEMBL12679798 | 0.72 | ALDH1A1 (0.55) | PTPN1ALDH1A1HSD17B10ALOX15PDE9A | |
| SCHEMBL24723205 | 0.71 | PTPN1 (0.51) | PTPN1ALDH1A1HSD17B10ALOX15KDM4E | |
| SCHEMBL21536932 | 0.70 | ALDH1A1 (0.37) | PTPN1ALDH1A1HSD17B10ALOX15PDE9A | |
| SCHEMBL1899869 | 0.69 | HTT (0.48) | ALDH1A1HSD17B10ALOX15MAPTMEN1 | |
| SCHEMBL16984845 | 0.68 | ALDH1A1 (0.55) | PTPN1ALDH1A1HSD17B10ALOX15PDE9A | |
| SCHEMBL12681373 | 0.68 | ALDH1A1 (0.55) | PTPN1ALDH1A1HSD17B10ALOX15PDE9A | |
| SCHEMBL21248636 | 0.67 | ALDH1A1 (0.47) | PTPN1ALDH1A1HSD17B10ALOX15PDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576398-A | POLYCARBODIIMIDES GRAFTED WITH CARBOXYLIC ANHYDRIDE AND EPOXY COMPOUND FOR MOLDING MATERIALS | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1996-11-19 | — | — | US | disclosed |