Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.55 |
| ▸ | RELA | Q04206 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
| ▸ | ACR | P10323 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23818249 | 0.98 | LMNA (0.54) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL16772395 | 0.93 | LMNA (0.63) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL6510953 | 0.91 | MAPT (0.50) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL4348938 | 0.88 | GAA (0.44) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL12926236 | 0.87 | MAPT (0.50) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL7660791 | 0.87 | THRB (0.50) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL7572221 | 0.85 | ESR1 (0.42) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL7573082 | 0.85 | ESR1 (0.42) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL7573334 | 0.85 | ESR1 (0.48) | LMNANPC1NFKB1NFKB2RELA | |
| SCHEMBL7574157 | 0.85 | ESR1 (0.48) | LMNANPC1NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749466-A1 | NOVEL POLYMERISABLE LIQUID-CRYSTALLINE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1996-12-27 | — | — | EP | disclosed |
| WO-1995024454-A1 | NOVEL POLYMERISABLE LIQUID-CRYSTALLINE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1995-09-14 | — | — | WO | disclosed |