SCHEMBL9061995

SCHEMBL9061995

O=C(O)CCP(=O)(O)CCC(=O)O.[LiH]

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 1/20 0.59
GRM6 O15303 1/20 0.59
GRM7 Q14831 1/20 0.59
GRM4 Q14833 1/20 0.59
LMNA P02545 4/20 0.44
ALKBH5 Q6P6C2 1/20 0.44
SUCNR1 Q9BXA5 1/20 0.44
EGLN1 Q9GZT9 1/20 0.44
GRM3 Q14832 2/20 0.43
FFAR3 O14843 1/20 0.43
HDAC3 O15379 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
FOLH1 Q04609 2/20 0.41
TSHR P16473 2/20 0.41
MEN1 O00255 1/20 0.41
HPGD P15428 1/20 0.41
BLM P54132 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2403116 0.97 GRM8 (0.61) GRM8GRM6GRM7GRM4LMNA
SCHEMBL338686 0.87 GRM8 (0.53) GRM8GRM6GRM7GRM4LMNA
SCHEMBL12145014 0.85 LMNA (0.52) GRM8GRM6GRM7GRM4LMNA
SCHEMBL340145 0.85 FFAR3 (0.55) GRM8GRM6GRM7GRM4FFAR3
SCHEMBL8844627 0.82 FFAR3 (0.50) GRM8GRM6GRM7GRM4LMNA
SCHEMBL338870 0.81 FFAR3 (0.50) GRM8GRM6GRM7GRM4LMNA
SCHEMBL339162 0.81 GABBR2 (0.57) GRM8GRM6GRM7GRM4FFAR3
SCHEMBL2290837 0.79 FFAR3 (0.48) GRM8GRM6GRM7GRM4LMNA
SCHEMBL3954142 0.79 FFAR3 (0.48) GRM8GRM6GRM7GRM4LMNA
SCHEMBL2378568 0.79 FFAR3 (0.48) GRM8GRM6GRM7GRM4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8302079-A None JP disclosed
JP-H08302079-A CRYSTALLINE POLYOLEFIN COMPOSITION CHISSO CORP 1996-11-19 JP disclosed