SCHEMBL9062147

SCHEMBL9062147

ClN(Cl)c1ccc(/C=N/N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
MEN1 O00255 6/20 0.48
KMT2A Q03164 6/20 0.48
ALDH1A1 P00352 6/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
MCL1 Q07820 1/20 0.46
USP2 O75604 1/20 0.46
POLB P06746 1/20 0.45
EIF4H Q15056 1/20 0.45
MAPT P10636 5/20 0.44
GAA P10253 3/20 0.44
HSP90AA1 P07900 1/20 0.44
G6PC1 P35575 4/20 0.41
MAPK1 P28482 4/20 0.40
HTT P42858 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9062150 1.00 CYP1A2 (0.50) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL332093 0.85 CYP1A2 (0.53) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL332094 0.85 CYP1A2 (0.53) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL987853 0.84 USP2 (0.55) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL987854 0.84 USP2 (0.55) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL17366375 0.83 G6PC1 (0.57) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL12637395 0.81 SMN1; SMN2 (0.53) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL331931 0.81 ALDH1A1 (0.62) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL331930 0.81 ALDH1A1 (0.62) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL19061995 0.81 CYP1A2 (0.53) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0632337-B1 Image forming method CANON KK (JP) 1996-09-04 EP disclosed
US-5480759-A ELECTROGRAPHY CANON KABUSHIKI KAISHA (JP) 1996-01-02 US disclosed
EP-0632337-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1995-01-04 EP disclosed