Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.51 |
| ▸ | CTSS | P25774 | 5/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4936593 | 1.00 | CTSK (0.51) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL1853923 | 1.00 | CTSK (0.51) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL3229583 | 0.89 | CTSK (0.49) | CTSKCTSS | |
| SCHEMBL3213512 | 0.89 | CTSK (0.49) | CTSKCTSS | |
| SCHEMBL28132863 | 0.88 | CTSK (0.48) | CTSKCTSS | |
| SCHEMBL28465534 | 0.88 | CTSK (0.48) | CTSKCTSS | |
| SCHEMBL4935587 | 0.88 | CTSK (0.48) | CTSKCTSS | |
| SCHEMBL6684772 | 0.88 | CA1 (0.49) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL13669545 | 0.88 | CTSK (0.54) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL29265449 | 0.87 | CA1 (0.42) | CTSKCTSSCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717040-A1 | Thiazine or thiazepine derivatives which inhibit NOS | Japan Tobacco Inc. (JP) | 1996-06-19 | — | — | EP | disclosed |