Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.46 |
| ▸ | MMP2 | P08253 | 5/20 | 0.46 |
| ▸ | MMP3 | P08254 | 5/20 | 0.46 |
| ▸ | MMP1 | P03956 | 3/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28132863 | 1.00 | CTSK (0.48) | CTSKCTSSGPR84MMP2MMP3 | |
| SCHEMBL28465534 | 1.00 | CTSK (0.48) | CTSKCTSSGPR84MMP2MMP3 | |
| SCHEMBL3213512 | 0.98 | CTSK (0.49) | CTSKCTSSGPR84MMP2MMP3 | |
| SCHEMBL3229583 | 0.98 | CTSK (0.49) | CTSKCTSSGPR84MMP2MMP3 | |
| SCHEMBL22661716 | 0.89 | CTSK (0.52) | CTSKCTSS | |
| SCHEMBL29789535 | 0.88 | CTSK (0.47) | CTSKCTSS | |
| SCHEMBL18993567 | 0.88 | CTSK (0.55) | CTSKCTSS | |
| SCHEMBL1853923 | 0.88 | CTSK (0.51) | CTSKCTSS | |
| SCHEMBL4936593 | 0.88 | CTSK (0.51) | CTSKCTSS | |
| SCHEMBL9062184 | 0.88 | CTSK (0.51) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312080-A1 | Novel dioctatin derivatives and production process thereof | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312080-A1 | Novel dioctatin derivatives and production process thereof | AKR7A2, HDHD5, DECR1 | CTSK 4665/4885CTSS 4683/4885GPR84 2834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.