Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.33 |
| ▸ | ITGAV | P06756 | 4/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9062879 | 0.88 | ALDH1A1 (0.35) | F2ITGB3ITGAVITGA2B | |
| SCHEMBL9066349 | 0.77 | F2 (0.42) | F2ITGB3ITGAVITGA2BF10 | |
| SCHEMBL9054950 | 0.74 | F2 (0.44) | F2ITGB3ITGAVITGA2B | |
| SCHEMBL9055325 | 0.74 | F2 (0.42) | F2ITGB3ITGAVITGA2BF10 | |
| SCHEMBL9054492 | 0.74 | F2 (0.43) | F2ITGB3ITGAVITGA2B | |
| SCHEMBL9058635 | 0.72 | F2 (0.34) | F2ITGB3ITGAVITGA2BF10 | |
| SCHEMBL9066345 | 0.72 | F2 (0.54) | F2F10LMNA | |
| SCHEMBL9064351 | 0.69 | F2 (0.43) | F2ITGB3ITGAVITGA2BF10 | |
| SCHEMBL9062397 | 0.68 | ALDH1A1 (0.42) | F2TSHRLMNA | |
| SCHEMBL9055899 | 0.67 | F2 (0.46) | F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002517-A1 | SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |