Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 3/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.31 |
| ▸ | ITGAV | P06756 | 4/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055946 | 0.89 | HTR6 (0.33) | F2ITGB3ITGAVITGA2BHTR6 | |
| SCHEMBL9062397 | 0.86 | ALDH1A1 (0.42) | F2ALDH1A1ALOX15MAPK1LMNA | |
| SCHEMBL9055255 | 0.84 | HTR6 (0.36) | F2ALDH1A1LMNAITGB3ITGAV | |
| SCHEMBL9062879 | 0.81 | ALDH1A1 (0.35) | F2ALDH1A1ALOX15MAPK1ITGB3 | |
| SCHEMBL9055655 | 0.80 | F2 (0.39) | F2ALDH1A1MAPK1ITGB3ITGAV | |
| SCHEMBL9064351 | 0.79 | F2 (0.43) | F2F10PRSS1LMNAPLAT | |
| SCHEMBL9055264 | 0.79 | F2 (0.43) | F2ALDH1A1F10PRSS1LMNA | |
| SCHEMBL9054934 | 0.79 | F2 (0.46) | F2F10PRSS1LMNAPLAT | |
| SCHEMBL9056137 | 0.78 | F2 (0.40) | F2ALDH1A1F10PRSS1LMNA | |
| SCHEMBL9055310 | 0.77 | F2 (0.40) | F2F10PRSS1LMNAPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002517-A1 | SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |