SCHEMBL906302

SCHEMBL906302

O=C(O)c1cc(C(=O)Cl)cc(C(=O)Cl)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 3/20 0.55
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
TTR P02766 2/20 0.50
LCK P06239 1/20 0.48
FYN P06241 1/20 0.48
TP53 P04637 2/20 0.48
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48
CA3 P07451 1/20 0.48
MAPT P10636 1/20 0.48
SELL P14151 1/20 0.48
HPGD P15428 1/20 0.48
SELP P16109 1/20 0.48
FUT4 P22083 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL93750 1.00 TPMT (0.55) TPMTCA12CA1CA2CA7
SCHEMBL29099600 1.00 TPMT (0.55) TPMTCA12CA1CA2CA7
SCHEMBL14829821 1.00 TPMT (0.55) TPMTCA12CA1CA2CA7
SCHEMBL28650829 0.92 DHODH (0.48) TPMTCA12CA1CA2CA7
SCHEMBL11707085 0.90 CA12 (0.68) TPMTCA12CA1CA2CA7
SCHEMBL12502026 0.90 CA12 (0.68) TPMTCA12CA1CA2CA7
SCHEMBL6133362 0.88 POLB (0.47) TPMTCA12CA1CA2CA7
Benzene SCHEMBL28576976 0.88 TDP1 (0.43) TPMTCA12CA1CA2CA7
SCHEMBL38576 0.87 ALDH1A1 (0.40) TPMTCA12CA1CA2CA7
Hydrochloric Acid SCHEMBL18918955 0.84 ALDH1A1 (0.39) TPMTCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112973473-A Reverse osmosis composite membrane resisting biological pollution and preparation method thereof 天津工业大学 2021-06-18 CN claimed
US-10137418-B2 Composite polyamide membrane made via interfacial polymerization using a blend of non-polar solvents DOW GLOBAL TECHNOLOGIES LLC (US) 2018-11-27 US claimed
EP-1274762-B1 POLYCARBONATE PREPARATION PROCESS DOW GLOBAL TECHNOLOGIES INC (US) 2005-05-11 EP claimed
EP-1254701-B1 Process of making microcapsules by interfacial polycondensation between polyoxyalkyleneamine and acid chlorides INST FRANCAIS DU PETROLE (FR) 2005-03-23 EP claimed
US-6706397-B2 PREPARING A WATER-INSOLUBLE ORGANIC PHASE OF ACID CHLORIDES, FORMING AN EMULSION OF ORGANIC PHASE IN AQUEOUS PHASE, ADDING EMULSION OF POLYOXYALKYLENE POLYAMINE, REACTING MONOMER TO FORM POLYAMIDE MEMBRANE AROUND EMULSIFIED ORGANIC PHASE INSTITUT FRANCAIS DU PETROLE (FR) 2004-03-16 US claimed
EP-1274762-A1 POLYCARBONATE PREPARATION PROCESS THE DOW CHEMICAL COMPANY (US) 2003-01-15 EP claimed
US-20020158356-A1 Process for manufacturing microcapsules by interfacial polycondensation with polyoxyalkyleneamine and acid chlorides INSTITUT FRANCAIS DU PETROLE (FR) 2002-10-31 US claimed
WO-2001077204-A1 POLYCARBONATE PREPARATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2001-10-18 WO claimed
US-6225436-B1 REACTING PHOSGENE AND DIHYDRIC PHENOL; ADDING ACYL HALIDE; ADDING A CHAIN TERMINATOR TO THE REACTION MIXTURE; COMPLETING POLYMERIZATION REACTION THE DOW CHEMICAL COMPANY 2001-05-01 US claimed
US-4659475-A SEPARATION; DESALINIZATION MIDWEST RESEARCH INSTITUTE (US) 1987-04-21 US claimed
US-11794149-B2 High flux, chlorine resistant coating for sulfate removal membranes TELEDYNE SCIENTIFIC & IMAGING, LLC (US) 2023-10-24 US disclosed
CN-113637210-B Gas-barrier moisture-permeable film and preparation method and application thereof 中国石油化工股份有限公司 2023-04-04 CN disclosed
EP-3144054-B1 POLYAMIDE TFC MEMBRANES PREPARED USING MONO-HYDROLYZED TRIMESOYL CHLORIDE NANOH2O INC (US) 2022-11-02 EP disclosed
EP-3144052-B1 HYBRID NANOPARTICLE TFC MEMBRANES NANOH2O INC (US) 2022-08-31 EP disclosed
CN-114749034-A Acid-resistant nanofiltration membrane with double-layer structure and preparation method and application thereof 新疆中泰创新技术研究院有限责任公司 2022-07-15 CN disclosed
EP-1274762-A1 POLYCARBONATE PREPARATION PROCESS THE DOW CHEMICAL COMPANY (US) 2003-01-15 EP disclosed
US-20020158356-A1 Process for manufacturing microcapsules by interfacial polycondensation with polyoxyalkyleneamine and acid chlorides INSTITUT FRANCAIS DU PETROLE (FR) 2002-10-31 US disclosed
WO-2001077204-A1 POLYCARBONATE PREPARATION PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2001-10-18 WO disclosed
US-6225436-B1 REACTING PHOSGENE AND DIHYDRIC PHENOL; ADDING ACYL HALIDE; ADDING A CHAIN TERMINATOR TO THE REACTION MIXTURE; COMPLETING POLYMERIZATION REACTION THE DOW CHEMICAL COMPANY 2001-05-01 US disclosed
US-4059565-A Process for producing a branched polycarbonate or poly(ester-carbonate) MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1977-11-22 US disclosed