SCHEMBL38576

SCHEMBL38576

O=C(Cl)c1cc(C(=O)Cl)cc(C(=O)Cl)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
TSHR P16473 4/20 0.39
TPMT P51580 2/20 0.36
ATM Q13315 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GLRA1 P23415 1/20 0.33
TTR P02766 1/20 0.33
HDAC8 Q9BY41 1/20 0.32
ALOX15 P16050 2/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
CES2 O00748 2/20 0.32
CES1 P23141 2/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL18918955 0.96 ALDH1A1 (0.39) ALDH1A1TSHRTPMTATMTDP1
Benzene SCHEMBL28576976 0.93 TDP1 (0.43) ALDH1A1TSHRTPMTATMTDP1
Ethane SCHEMBL29138437 0.93 ALDH1A1 (0.37) ALDH1A1TSHRTPMTATMTDP1
SCHEMBL29201943 0.93 ALDH1A1 (0.37) ALDH1A1TSHRTPMTATMTDP1
Acetone SCHEMBL28498158 0.90 LMNA (0.38) ALDH1A1TSHRTPMTATMTDP1
Cyclohexane SCHEMBL27887761 0.90 ALDH1A1 (0.36) ALDH1A1TSHRTPMTATMTDP1
SCHEMBL8060297 0.90 ALDH1A1 (0.36) ALDH1A1TSHRTPMTATMTDP1
SCHEMBL1962624 0.90 TDP1 (0.42) ALDH1A1TSHRATMTDP1L3MBTL1
SCHEMBL11705603 0.87 CA12 (0.50) ALDH1A1TSHRGLRA1CA12CA1
SCHEMBL93750 0.87 TPMT (0.55) ALDH1A1TSHRTPMTTDP1TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 15086 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122076260-A High-hydrophilicity organic solvent reverse osmosis membrane and preparation method thereof 2026-05-26 CN claimed
CN-122076252-A SD membrane based on synergistic alcohol phase system interfacial polymerization and preparation method thereof 2026-05-26 CN claimed
CN-115532062-B Enhanced chlorine-resistant reverse osmosis membrane and preparation method thereof Hunan Aowui Membrane Technology Co.,Ltd. (CN) 2026-05-26 CN claimed
US-12636622-B2 Preparation method of reverse osmosis composite membrane and reverse osmosis composite membrane prepared thereby Hunan Ovay Film Technology Co., Ltd. (CN) 2026-05-26 US claimed
CN-117443213-B Preparation method for preparing composite nanofiltration membrane by mixed solvent electrostatic spinning Changzhou University (CN) 2026-05-26 CN claimed
CN-122076251-A Preparation method of high-power concentrated SD membrane and high-power concentrated SD membrane 2026-05-26 CN claimed
CN-119793245-B Application of adamantane-1, 3-diamine in preparing reverse osmosis membrane with controllable desalination performance, reverse osmosis membrane, preparation method and application The Institute Of Seawater Desalination And Multipurpose Utilization, Mnr (tianjin) (CN) 2026-05-26 CN claimed
CN-122076263-A Preparation method of 3D electrostatic spray printing positively charged nanofiltration membrane 2026-05-26 CN claimed
CN-120479205-B Preparation method of polyamide nanofiltration membrane containing titanium dioxide TAIZHOU HEYI NEW MATERIAL TECHNOLOGY Co.,Ltd. (CN) 2026-05-26 CN claimed
WO-2026102596-A1 POLYAMIDE COMPOSITE FILM AND PREPARATION METHOD THEREFOR 苏州苏瑞膜纳米科技集团有限公司 2026-05-21 WO claimed
EP-0056175-A1 Ion-permeable composite membrane and its use in selective separation TEIJIN LIMITED (JP) 1982-07-21 EP claimed
US-4302336-A A CROSSLINKED AMINE-MODIFIED ACRYLIC POLYMER; DESALTING OF BRINES BY REVERSE OSMOSIS TEIJIN LIMITED (JP) 1981-11-24 US claimed
EP-0031730-A2 The improved semipermeable composite membranes and process for their production TEIJIN LIMITED (JP) 1981-07-08 EP claimed
US-4265745-A CROSSLINKED POLYEPOXY COMPOUND AND POLYAMINO COMPOUND AND A MICROPOROUS SUBSTRATE PROVIDES FLEXIBILITY AND CHEMICAL RESISTANCE TEIJIN LIMITED (JP) 1981-05-05 US claimed
US-4259183-A POLYAMIDE FROM PIPERAZINE AND TRIACYL HALIDE MIDWEST RESEARCH INSTITUTE (US) 1981-03-31 US claimed
EP-0022827-A1 REVERSE OSMOSIS MEMBRANE Midwest Research Institute (US) 1981-01-28 EP claimed
EP-0014054-A1 Process for the production of a reverse osmosis membrane, reverse osmosis membrane thus produced, and use of such membrane in a desalination process Midwest Research Institute (US) 1980-08-06 EP claimed
WO-1980001464-A1 REVERSE OSMOSIS MEMBRANE MIDWEST RESEARCH INST (US) 1980-07-24 WO claimed
EP-0008945-A2 Semipermeable composite membrane, process for producing said membrane, and method of desalination using said membrane TEIJIN LIMITED (JP) 1980-03-19 EP claimed
US-4120954-A COMPLEMENT INHIBITORS AMERICAN CYANAMID COMPANY (US) 1978-10-17 US claimed