Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2386838 | 0.97 | HSD11B1 (0.42) | HSD11B1CYP2C9GRIN2DGRIN3BGRIN1 | |
| SCHEMBL23451146 | 0.85 | HSD11B1 (0.32) | HSD11B1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8148768 | 0.83 | — | — | |
| SCHEMBL21425644 | 0.80 | HSD11B1 (0.35) | HSD11B1CYP2C9 | |
| SCHEMBL22416817 | 0.78 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL1603764 | 0.77 | HSD11B1 (0.41) | HSD11B1CYP2C9GRIN2DGRIN3BGRIN1 | |
| SCHEMBL21650459 | 0.75 | HSD11B1 (0.44) | HSD11B1CYP2C9CXCR3 | |
| Hydrochloric Acid SCHEMBL7527143 | 0.75 | HSD11B1 (0.39) | HSD11B1CYP2C9GRIN2DGRIN3BGRIN1 | |
| SCHEMBL23790989 | 0.73 | CYP2C9 (0.36) | HSD11B1CYP2C9GRIN2DGRIN3BGRIN1 | |
| SCHEMBL24245369 | 0.73 | CYP2C9 (0.36) | HSD11B1CYP2C9GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045534-A2 | CHROMAN DERIVATIVES FOR THE REDUCTION OF INFLAMMATION SYMPTOMS | GALILEO PHARMACEUTICALS, INC. (US) | 2004-06-03 | — | — | WO | claimed |
| US-20040097433-A1 | Chroman derivatives for the reduction of inflammation symptoms | MONSANTO TECHNOLOGY LLC | 2004-05-20 | — | — | US | claimed |
| US-5932566-A | Ansamycin derivatives as antioncogene and anticancer agents | PFIZER INC. (US) | 1999-08-03 | — | — | US | claimed |
| EP-0706516-A1 | ANSAMYCIN DERIVATIVES AS ANTIONCOGENE AND ANTICANCER AGENTS | PFIZER INC. (US) | 1996-04-17 | — | — | EP | claimed |
| WO-1995001342-A1 | ANSAMYCIN DERIVATIVES AS ANTIONCOGENE AND ANTICANCER AGENTS | PFIZER INC. (US) | 1995-01-12 | — | — | WO | claimed |
| US-20260001846-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | SERVIER LAB (FR) | 2026-01-01 | — | — | US | disclosed |
| EP-4551566-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | Les Laboratoires Servier (FR) | 2025-05-14 | — | — | EP | disclosed |
| CN-119816491-A | New spirocyclohexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors | 法国施维雅药厂 | 2025-04-11 | — | — | CN | disclosed |
| WO-2024238396-A1 | NMDA LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2024-11-21 | — | — | WO | disclosed |
| CN-118963059-A | Photoresist composition, coated substrate comprising photoresist composition, and method of forming electronic device | 罗门哈斯电子材料有限责任公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-106933030-B | Photoresist composition, coated substrate comprising photoresist composition, and method of forming electronic device | 罗门哈斯电子材料有限责任公司 | 2024-08-16 | — | — | CN | disclosed |
| US-11960206-B2 | Photoresist composition, coated substrate including the photoresist composition, and method of forming electronic device | Rohm and Hass Electronic Materials LLC (US) | 2024-04-16 | — | — | US | disclosed |
| US-5514683-A | LIGANDS FKOR CHOLECYSTOKININ OR GASTRIN RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 1996-05-07 | — | — | US | disclosed |
| EP-0706516-A1 | ANSAMYCIN DERIVATIVES AS ANTIONCOGENE AND ANTICANCER AGENTS | PFIZER INC. (US) | 1996-04-17 | — | — | EP | disclosed |
| US-5488055-A | ADMINISTERING GMP HOSPHODIESTERASE INHIBITORS FOR TREATMENT OF CONGESTIVE HEART FAILURE AND CARDIOVASCULAR DISORDERS | SANOFI WINTHROP INC. (US) | 1996-01-30 | — | — | US | disclosed |
| WO-1995001342-A1 | ANSAMYCIN DERIVATIVES AS ANTIONCOGENE AND ANTICANCER AGENTS | PFIZER INC. (US) | 1995-01-12 | — | — | WO | disclosed |
| EP-0626942-A1 | BICYCLO 2.2.2.]OCTANE DERIVATIVES AS CHOLESTOCYSTOKININ INHIBITORS. | BLACK JAMES FOUNDATION (GB) | 1994-12-07 | — | — | EP | disclosed |
| WO-1993016982-A1 | BICYCLO[2.2.2.]OCTANE DERIVATIVES AS CHOLESTOCYSTOKININ INHIBITORS | JAMES BLACK FOUNDATION LIMITED (GB) | 1993-09-02 | — | — | WO | disclosed |
| WO-1992020336-A2 | NOVEL CHOLESTEROL LOWERING COMPOUNDS | MERCK & CO., INC. (US) | 1992-11-26 | — | — | WO | disclosed |
| EP-0512865-A2 | Novel cholesterol lowering compounds | MERCK & CO. INC. (US) | 1992-11-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11960206-B2 | Photoresist composition, coated substrate including the photoresist composition, and method of forming electronic device | PPIG, PARG, EEF1G | HSD11B1 3177/4885CYP2C9 397/4885GRIN2D 103/4885 |
| US-20260001846-A1 | SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | BCL2, BCL2A1, BAX | HSD11B1 135/4885CYP2C9 2339/4885GRIN2D 3869/4885 |
| US-20040097433-A1 | Chroman derivatives for the reduction of inflammation symptoms | CCL2, MPO, MB | HSD11B1 854/4885CYP2C9 589/4885GRIN2D 4310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.