Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | STAT3 | P40763 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28702138 | 0.86 | ABCB1 (0.48) | KDM4EGAAHSD17B10ALDH1A1LMNA | |
| SCHEMBL28040137 | 0.85 | TRPM8 (0.51) | MAPTNPSR1XBP1MEN1ALDH1A1 | |
| SCHEMBL28040136 | 0.85 | TRPM8 (0.51) | MAPTNPSR1XBP1MEN1ALDH1A1 | |
| Vanillin SCHEMBL28143528 | 0.84 | ALDH1A1 (0.52) | KDM4EGAAMAPTCYP2D6CYP1A2 | |
| SCHEMBL18585887 | 0.84 | ALDH1A1 (0.49) | KDM4EGAAMAPTNPSR1CA12 | |
| SCHEMBL813796 | 0.82 | ALDH1A1 (0.46) | KDM4EGAAMAPTNPSR1TSHR | |
| Vanillin SCHEMBL28030699 | 0.82 | ALDH1A1 (0.54) | KDM4EGAAMAPTNPSR1EPHX2 | |
| SCHEMBL11886539 | 0.81 | TRPV1 (0.61) | KDM4EGAAMAPTNPSR1EPHX2 | |
| SCHEMBL11886538 | 0.81 | TRPV1 (0.61) | KDM4EGAAMAPTNPSR1EPHX2 | |
| SCHEMBL16616743 | 0.80 | ALDH1A1 (0.56) | KDM4EGAAMAPTNPSR1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3344265-A1 | TOPICAL ANTIVIRAL COMPOSITIONS | Topical Remedy, LLC (US) | 2018-07-11 | — | — | EP | disclosed |
| WO-2017040844-A1 | TOPICAL ANTIVIRAL COMPOSITIONS | TOPICAL REMEDY, LLC (US) | 2017-03-09 | — | — | WO | disclosed |
| EP-0742012-A2 | Pharmaceutical composition containing substance inhibiting HSP47 production | Kureha Chemical Industry Co., Ltd. (JP) | 1996-11-13 | — | — | EP | disclosed |