⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9062911 | 0.82 | — | — | |
| SCHEMBL20658954 | 0.80 | SPHK2 (0.48) | — | |
| SCHEMBL17817177 | 0.78 | SPHK2 (0.52) | — | |
| SCHEMBL5690098 | 0.73 | — | — | |
| SCHEMBL10424965 | 0.73 | — | — | |
| Bicarbonate SCHEMBL14839779 | 0.71 | GPR84 (0.52) | — | |
| Hydrochloric Acid SCHEMBL27850514 | 0.71 | — | — | |
| SCHEMBL10144096 | 0.69 | — | — | |
| SCHEMBL18804411 | 0.67 | — | — | |
| SCHEMBL436447 | 0.67 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | claimed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | claimed |
| CN-117597184-A | MBZA/PEG diethyl ether based liquid solvent CO in a rotating packed bed 2 Capturing | 研究三角协会 | 2024-02-23 | — | — | CN | disclosed |
| CN-111974166-A | Regenerable solvent mixtures for acid gas separation | 三角形研究学会 | 2020-11-24 | — | — | CN | disclosed |
| CN-104271219-B | Regenerable solvent mixtures for acid gas separation | 三角形研究学会 | 2020-08-21 | — | — | CN | disclosed |
| CN-108026191-B | Biocidal mixtures | 朗盛德国有限责任公司 | 2020-05-29 | — | — | CN | disclosed |
| WO-1996017612-A1 | USE OF SUBSTITUTED PHENYLAMIDINE AND PHENYLGUANIDINE COMPOUNDS FOR THE TREATMENT OF CEREBRAL AND CARDIAC ISCHAEMIA, CONVULSION AND SICKLE CELL ANAEMIA | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | disclosed |
| US-5373008-A | Phenylamidine and phenylguanidine derivatives and their use as anti-diabetic agents | THE BOOTS COMPANT PLC. (GB) | 1994-12-13 | — | — | US | disclosed |
| US-5223498-A | Hypoglycemic agents | THE BOOTS COMPANY PLC (GB) | 1993-06-29 | — | — | US | disclosed |
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | disclosed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | disclosed |