Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 11/20 | 0.61 |
| ▸ | HTR2C | P28335 | 3/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22049110 | 0.83 | HTR2A (0.61) | HTR2AHTR2CSLC6A2SLC6A4HRH1 | |
| SCHEMBL21996453 | 0.83 | HTR2A (0.61) | HTR2AHTR2CSLC6A2SLC6A4HRH1 | |
| SCHEMBL8617506 | 0.82 | TBXA2R (0.46) | HTR2AHTR2CSLC6A2SLC6A4DRD2 | |
| SCHEMBL9063943 | 0.79 | TBXA2R (0.41) | HTR2AHTR2CSLC6A2SLC6A4HRH1 | |
| SCHEMBL7509159 | 0.79 | TBXA2R (0.41) | HTR2AHTR2CSLC6A2SLC6A4HRH1 | |
| SCHEMBL7520603 | 0.74 | DRD2 (0.39) | HTR2AHTR2CSLC6A2SLC6A4HRH1 | |
| SCHEMBL6938853 | 0.73 | TBXA2R (0.45) | DRD2DRD3TBXA2R | |
| SCHEMBL9062919 | 0.71 | TBXA2R (0.36) | HTR2AHTR2CSLC6A2SLC6A4DRD2 | |
| SCHEMBL11611762 | 0.71 | HTR2A (0.64) | HTR2AHTR2CHRH1RETTBXA2R | |
| SCHEMBL8798181 | 0.70 | TBXA2R (0.36) | HTR2AHTR2CSLC6A2SLC6A4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742208-A1 | 2-Ureido-benzamide derivatives | GRELAN PHARMACEUTICAL CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |