⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18241826 | 0.83 | ALDH1A1 (0.44) | — | |
| SCHEMBL8734714 | 0.73 | — | — | |
| SCHEMBL203137 | 0.69 | — | — | |
| SCHEMBL8734710 | 0.67 | — | — | |
| Methane SCHEMBL205249 | 0.67 | ALDH1A1 (0.41) | — | |
| SCHEMBL49924 | 0.67 | — | — | |
| SCHEMBL7115711 | 0.65 | — | — | |
| SCHEMBL7980090 | 0.65 | — | — | |
| SCHEMBL11579035 | 0.65 | ALDH1A1 (0.39) | — | |
| SCHEMBL6881712 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0362145-B1 | Crosslinked siloxane-urethane polymer contact lens | CIBA GEIGY AG (CH) | 1996-01-03 | — | — | EP | disclosed |
| US-5426158-A | Interpenetrating polymer network with vinyl polymer | CIBA-GEIGY CORP. (US) | 1995-06-20 | — | — | US | disclosed |
| EP-0367720-B1 | Novel polysiloxane-polyurethanes and contact lenses thereof | CIBA GEIGY AG (CH) | 1994-07-20 | — | — | EP | disclosed |
| US-4983702-A | Crosslinked siloxane-urethane polymer contact lens | CIBA-GEIGY CORPORATION (US) | 1991-01-08 | — | — | US | disclosed |
| US-4962178-A | 0XYGEN PERMEABLE MEMBRANE | CIBA-GEIGY CORPORATION (US) | 1990-10-09 | — | — | US | disclosed |
| EP-0367720-A2 | Novel polysiloxane-polyurethanes and contact lenses thereof | CIBA-GEIGY AG (CH) | 1990-05-09 | — | — | EP | disclosed |
| EP-0362145-A2 | Crosslinked siloxane-urethane polymer contact lens | CIBA-GEIGY AG (CH) | 1990-04-04 | — | — | EP | disclosed |