Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1289275 | 0.86 | FAAH (0.66) | FAAHFFAR4FFAR1MEN1KMT2A | |
| SCHEMBL29150180 | 0.85 | FFAR4 (0.70) | FAAHFFAR4FFAR1MEN1KMT2A | |
| SCHEMBL8376232 | 0.85 | FFAR4 (0.51) | FAAHFFAR4FFAR1MEN1KMT2A | |
| SCHEMBL9063816 | 0.85 | FFAR4 (0.70) | FAAHFFAR4FFAR1MEN1KMT2A | |
| SCHEMBL17199795 | 0.84 | ANPEP (0.49) | FAAHFFAR4FFAR1GPR84ANPEP | |
| SCHEMBL7320330 | 0.84 | ANPEP (0.49) | FAAHFFAR4FFAR1GPR84ANPEP | |
| SCHEMBL13833063 | 0.84 | ANPEP (0.49) | FAAHFFAR4FFAR1GPR84ANPEP | |
| SCHEMBL11677240 | 0.84 | ANPEP (0.49) | FAAHFFAR4FFAR1GPR84ANPEP | |
| SCHEMBL1270381 | 0.84 | ANPEP (0.49) | FAAHFFAR4FFAR1GPR84ANPEP | |
| SCHEMBL16859680 | 0.84 | ANPEP (0.49) | FAAHFFAR4FFAR1GPR84ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719267-A1 | SECOND MESSENGER CELL SIGNALING INHIBITORS | CELL THERAPEUTICS, INC. (US) | 1996-07-03 | — | — | EP | disclosed |
| EP-0719267-A4 | SECOND MESSENGER CELL SIGNALING INHIBITORS | CELL THERAPEUTICS INC (US) | 1996-02-16 | — | — | EP | disclosed |
| WO-1994022863-A9 | SECOND MESSENGER CELL SIGNALING INHIBITORS | — | 1994-12-22 | — | — | WO | disclosed |
| WO-1994022863-A1 | SECOND MESSENGER CELL SIGNALING INHIBITORS | CELL THERAPEUTICS, INC. (US) | 1994-10-13 | — | — | WO | disclosed |