Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905393 | 0.80 | CFTR (0.50) | ALDH1A1SMN1; SMN2KDM4EHPGDMCL1 | |
| SCHEMBL9856614 | 0.79 | SLC6A3 (0.53) | ALDH1A1SMN1; SMN2KDM4EHPGDGAA | |
| SCHEMBL6503402 | 0.79 | SLC6A3 (0.51) | ALDH1A1SMN1; SMN2KDM4EFFAR4LMNA | |
| SCHEMBL6491174 | 0.79 | SLC6A3 (0.55) | ALDH1A1SMN1; SMN2KDM4EHPGDUSP2 | |
| SCHEMBL6502875 | 0.79 | SLC6A3 (0.55) | ALDH1A1SMN1; SMN2KDM4EHPGDUSP2 | |
| SCHEMBL6493029 | 0.79 | SLC6A3 (0.55) | ALDH1A1SMN1; SMN2KDM4EHPGDUSP2 | |
| SCHEMBL6502878 | 0.79 | SLC6A3 (0.55) | ALDH1A1SMN1; SMN2KDM4EHPGDUSP2 | |
| Hydrochloric Acid SCHEMBL6501875 | 0.77 | SLC6A3 (0.54) | ALDH1A1SMN1; SMN2KDM4EHPGDUSP2 | |
| Acetic Acid SCHEMBL15333210 | 0.69 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2KDM4EHPGDUSP2 | |
| SCHEMBL13888048 | 0.69 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536083-B1 | Process for the synthesis of dialkyl succinylsuccinate esters and their conversion to dialkyl 2,5-diarylamino-3,6-dihydroterephthalate esters | CIBA GEIGY AG (CH) | 1996-03-06 | — | — | EP | disclosed |
| EP-0536083-A1 | Process for the synthesis of dialkyl succinylsuccinate esters and their conversion to dialkyl 2,5-diarylamino-3,6-dihydroterephthalate esters | CIBA-GEIGY AG (CH) | 1993-04-07 | — | — | EP | disclosed |