⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1056434 | 0.79 | — | — | |
| SCHEMBL146172 | 0.74 | — | — | |
| SCHEMBL4725794 | 0.74 | — | — | |
| SCHEMBL9484394 | 0.71 | NOS1 (0.31) | — | |
| SCHEMBL4291749 | 0.70 | — | — | |
| SCHEMBL1805649 | 0.66 | — | — | |
| SCHEMBL22194101 | 0.66 | — | — | |
| SCHEMBL165724 | 0.65 | — | — | |
| Bromide SCHEMBL6350033 | 0.64 | — | — | |
| SCHEMBL10583341 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388028-B1 | Curable norbornenyl functional silicone formulations | LOCTITE CORP (US) | 1996-04-10 | — | — | EP | disclosed |
| US-5266670-A | Reaction of norbornene compound with silane and hydrosilation | LOCTITE CORPORATION (US) | 1993-11-30 | — | — | US | disclosed |
| US-5171816-A | Curable by hydrosilation in presence of polymerization catalyst | LOCTITE CORPORATION (US) | 1992-12-15 | — | — | US | disclosed |
| US-5034490-A | Silicones with norbornene groups and thiol groups to cure by hydrosilation | LOCTITE CORPORATION (US) | 1991-07-23 | — | — | US | disclosed |