Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1990423 | 0.80 | EPHX2 (0.39) | EPHX2NR1H4CYP2C19 | |
| SCHEMBL1626481 | 0.79 | AKR1C3 (0.51) | AKR1C3AKR1C2SLC22A12CYP2C19MAP4K4 | |
| SCHEMBL4517620 | 0.79 | CYP2C19 (0.43) | EPHX2NR1H4CYP2C19RXRARXRB | |
| SCHEMBL9063833 | 0.76 | AKR1C3 (0.49) | AKR1C3AKR1C2SLC22A12CYP2C19MAP4K4 | |
| SCHEMBL9139847 | 0.76 | LTB4R (0.43) | AKR1C3AKR1C2LTB4RLTB4R2 | |
| SCHEMBL9063864 | 0.76 | LTB4R (0.42) | AKR1C3AKR1C2LTB4RLTB4R2 | |
| SCHEMBL9063301 | 0.76 | LTB4R (0.42) | AKR1C3AKR1C2LTB4RLTB4R2 | |
| SCHEMBL9063294 | 0.76 | LTB4R (0.43) | AKR1C3AKR1C2LTB4RLTB4R2 | |
| SCHEMBL1626272 | 0.75 | AKR1C3 (0.63) | AKR1C3AKR1C2SLC22A12MAP4K4APP | |
| SCHEMBL8848023 | 0.74 | APP (0.44) | AKR1C3AKR1C2SLC22A12LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641760-B1 | PHENYLALKANOIC ACID DERIVATIVE, PRODUCTION THEREOF, AND SEPARATION OF OPTICAL ISOMERS THEREOF | HISAMITSU PHARMACEUTICAL CO (JP) | 1996-11-06 | — | — | EP | disclosed |
| US-5434292-A | Phenylalkanoic acid derivatives, process for producing the same and process for separating optical isomers thereof | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1995-07-18 | — | — | US | disclosed |
| EP-0641760-A1 | PHENYLALKANOIC ACID DERIVATIVE, PRODUCTION THEREOF, AND SEPARATION OF OPTICAL ISOMERS THEREOF | Hisamitsu Pharmaceutical Co., Inc. (JP) | 1995-03-08 | — | — | EP | disclosed |