Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 7/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.41 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9063864 | 1.00 | LTB4R (0.42) | LTB4RLTB4R2PTGS1PTGS2MT-CO1 | |
| SCHEMBL9139847 | 0.98 | LTB4R (0.43) | LTB4RLTB4R2PTGS1PTGS2MT-CO1 | |
| SCHEMBL9063294 | 0.98 | LTB4R (0.43) | LTB4RLTB4R2PTGS1PTGS2MT-CO1 | |
| SCHEMBL9063541 | 0.77 | PTGS2 (0.44) | LTB4RLTB4R2PTGS1PTGS2CYP3A4 | |
| SCHEMBL9063302 | 0.77 | PTGS1 (0.64) | PTGS1PTGS2MT-CO1MT-CO2AKR1C3 | |
| SCHEMBL9063283 | 0.77 | PTGS1 (0.64) | PTGS1PTGS2MT-CO1MT-CO2AKR1C3 | |
| SCHEMBL9063281 | 0.77 | PTGS1 (0.64) | PTGS1PTGS2MT-CO1MT-CO2AKR1C3 | |
| SCHEMBL9064265 | 0.76 | PTGS1 (0.43) | LTB4RLTB4R2PTGS1PTGS2CYP3A4 | |
| SCHEMBL9064202 | 0.76 | AKR1C3 (0.44) | LTB4RLTB4R2AKR1C3AKR1C2 | |
| SCHEMBL9063532 | 0.74 | PTGS1 (0.61) | PTGS1PTGS2MT-CO1MT-CO2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641760-B1 | PHENYLALKANOIC ACID DERIVATIVE, PRODUCTION THEREOF, AND SEPARATION OF OPTICAL ISOMERS THEREOF | HISAMITSU PHARMACEUTICAL CO (JP) | 1996-11-06 | — | — | EP | disclosed |
| US-5434292-A | Phenylalkanoic acid derivatives, process for producing the same and process for separating optical isomers thereof | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1995-07-18 | — | — | US | disclosed |
| EP-0641760-A1 | PHENYLALKANOIC ACID DERIVATIVE, PRODUCTION THEREOF, AND SEPARATION OF OPTICAL ISOMERS THEREOF | Hisamitsu Pharmaceutical Co., Inc. (JP) | 1995-03-08 | — | — | EP | disclosed |