Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17785970 | 0.84 | ACE2 (0.50) | ACE2ANPEPERAP2HSD17B10CXCR4 | |
| SCHEMBL9064233 | 0.84 | ACE2 (0.60) | ACE2ANPEPERAP2HSD17B10CXCR4 | |
| SCHEMBL1264196 | 0.82 | POLB (0.41) | ANPEPERAP2HSD17B10CXCR4RAD52 | |
| SCHEMBL26114177 | 0.79 | ANPEP (0.50) | ACE2ANPEPERAP2HSD17B10CXCR4 | |
| SCHEMBL8603364 | 0.78 | ANPEP (0.49) | ACE2ANPEPERAP2HSD17B10CXCR4 | |
| Methylpiperazine SCHEMBL28849278 | 0.76 | ACE2 (0.42) | ACE2ANPEPERAP2HSD17B10MEN1 | |
| SCHEMBL8306633 | 0.75 | HSD17B10 (0.46) | ACE2ANPEPERAP2HSD17B10CXCR4 | |
| SCHEMBL302850 | 0.75 | ACE2 (0.72) | ACE2ANPEPERAP2HSD17B10CXCR4 | |
| SCHEMBL11580070 | 0.75 | ACE2 (0.59) | ACE2ANPEPERAP2HSD17B10CXCR4 | |
| SCHEMBL3522883 | 0.75 | HSD17B10 (0.53) | ACE2ANPEPERAP2HSD17B10CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017880-A1 | NOVEL POLYURETHANE TOUGHENER, THERMOSETTING RESIN COMPOSITIONS AND ADHESIVES | THE DEXTER CORPORATION (US) | 1996-06-13 | — | — | WO | disclosed |