Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961513 | 0.94 | CHRM1 (0.40) | CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL9459080 | 0.78 | — | — | |
| SCHEMBL9459083 | 0.77 | CHRM1 (0.42) | CHRM2CHRM1 | |
| SCHEMBL9458774 | 0.74 | CHRM1 (0.40) | CHRM2CHRM1 | |
| SCHEMBL9458552 | 0.72 | CHRM2 (0.42) | CHRM2CHRM1 | |
| SCHEMBL9458898 | 0.71 | — | — | |
| SCHEMBL9585060 | 0.71 | CHRNA7 (0.41) | — | |
| SCHEMBL2968389 | 0.71 | CHRNA7 (0.41) | — | |
| SCHEMBL8961518 | 0.71 | CHRNA7 (0.41) | — | |
| SCHEMBL9710931 | 0.71 | CHRNA7 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327155-A2 | Pyrazines, pyrimidines and pyridazines, useful in the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1989-08-09 | — | — | EP | claimed |
| US-5574028-A | SEDATIVES | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |
| US-5260293-A | Simulate central muscarinic acetlycholine receptors | MERCK SHARP & DOHME LIMITED (GB) | 1993-11-09 | — | — | US | disclosed |
| EP-0327155-A2 | Pyrazines, pyrimidines and pyridazines, useful in the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1989-08-09 | — | — | EP | disclosed |