Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064276 | 0.94 | CHRM2 (0.35) | CHRM1CHRM2 | |
| SCHEMBL9459083 | 0.84 | CHRM1 (0.42) | CHRM1CHRM2 | |
| SCHEMBL9458552 | 0.79 | CHRM2 (0.42) | CHRM1CHRM2 | |
| SCHEMBL9458763 | 0.76 | CHRM2 (0.39) | CHRM1CHRM2 | |
| SCHEMBL9584936 | 0.73 | CHRM2 (0.41) | CHRM1CHRM2 | |
| SCHEMBL9459002 | 0.72 | CHRM2 (0.40) | CHRM1CHRM2 | |
| SCHEMBL9458858 | 0.72 | CHRM2 (0.47) | CHRM2 | |
| Hydrochloric Acid SCHEMBL9459080 | 0.71 | — | — | |
| SCHEMBL9458919 | 0.69 | CHRM2 (0.40) | CHRM2 | |
| SCHEMBL7921990 | 0.68 | CHRM2 (0.54) | CHRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0327155-A2 | Pyrazines, pyrimidines and pyridazines, useful in the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1989-08-09 | — | — | EP | claimed |
| US-5574053-A | Method for treating anxiety | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |
| US-5574029-A | Method for treating anxiety | ELI LILLY AND COMPANY (US) | 1996-11-12 | — | — | US | disclosed |
| US-5260293-A | Simulate central muscarinic acetlycholine receptors | MERCK SHARP & DOHME LIMITED (GB) | 1993-11-09 | — | — | US | disclosed |
| EP-0327155-A2 | Pyrazines, pyrimidines and pyridazines, useful in the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1989-08-09 | — | — | EP | disclosed |