Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 2/20 | 0.53 |
| ▸ | TTR | P02766 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374224 | 0.90 | TTR (0.61) | CYP3A4SMN1; SMN2GPR35PARP1CA12 | |
| SCHEMBL30553550 | 0.90 | TTR (0.61) | CYP3A4SMN1; SMN2GPR35PARP1CA12 | |
| SCHEMBL3106666 | 0.83 | SMN1; SMN2 (0.59) | CYP3A4SMN1; SMN2PARP1ALDH1A1LMNA | |
| SCHEMBL6570802 | 0.83 | CYP3A4 (0.59) | CYP3A4SMN1; SMN2GPR35PARP1TTR | |
| SCHEMBL4638638 | 0.82 | SMN1; SMN2 (0.57) | CYP3A4SMN1; SMN2PARP1ALDH1A1LMNA | |
| SCHEMBL4056647 | 0.82 | SMN1; SMN2 (0.57) | CYP3A4SMN1; SMN2PARP1ALDH1A1LMNA | |
| SCHEMBL11808827 | 0.82 | GPR35 (0.56) | GPR35CA12CA1CA2CA9 | |
| SCHEMBL19436436 | 0.81 | CYP3A4 (0.52) | CYP3A4SMN1; SMN2GPR35PARP1TTR | |
| SCHEMBL503443 | 0.81 | CASP6 (0.62) | GPR35ERN1TTRALDH1A1LMNA | |
| SCHEMBL20066388 | 0.80 | SMN1; SMN2 (0.50) | CYP3A4SMN1; SMN2GPR35PARP1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514676-A | TO INHIBIT THE FORMATION OF ADVANCED GLYCOSLYATION PRODUCTS BY THE NONENZYMATIC CROSSLINKING OF PROTEINS WITH REDUCING SUGARS, USED IN FOOD PRESERVATION AND TO PREVENT PROTEIN AGING IN COLLAGEN OR LENSES IN THE EYE PRESERVATION | THE ROCKEFELLER UNIVERSITY (US) | 1996-05-07 | — | — | US | disclosed |