SCHEMBL9064385

SCHEMBL9064385

O=C(O)C(Cc1ccccc1Br)=C(Cc1ccccc1Br)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
CA12 O43570 4/20 0.44
CA1 P00915 4/20 0.44
CA2 P00918 4/20 0.44
CA9 Q16790 4/20 0.44
GPR52 Q9Y2T5 1/20 0.44
SIGMAR1 Q99720 1/20 0.42
AKR1B1 P15121 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
MAPK8 P45983 1/20 0.42
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 1/20 0.41
IDO1 P14902 1/20 0.41
CTBP2 P56545 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
FFAR1 O14842 1/20 0.41
FFAR4 Q5NUL3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9064608 1.00 ALDH1A1 (0.45) ALDH1A1CA12CA1CA2CA9
SCHEMBL9064382 1.00 ALDH1A1 (0.45) ALDH1A1CA12CA1CA2CA9
SCHEMBL9359428 0.87 FFAR1 (0.49) ALDH1A1CA12CA1CA2CA9
SCHEMBL9358917 0.87 FFAR1 (0.49) ALDH1A1CA12CA1CA2CA9
SCHEMBL4411791 0.83 CA12 (0.47) ALDH1A1CA12CA1CA2CA9
SCHEMBL30565097 0.83 AKR1B1 (0.61) ALDH1A1CA12CA1CA2CA9
SCHEMBL286410 0.83 AKR1B1 (0.61) ALDH1A1CA12CA1CA2CA9
SCHEMBL29674787 0.83 AKR1B1 (0.61) ALDH1A1CA12CA1CA2CA9
SCHEMBL9355175 0.82 CA12 (0.41) ALDH1A1CA12CA1CA2CA9
Hydrochloric Acid SCHEMBL2532034 0.81 AKR1B1 (0.59) ALDH1A1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0540003-B1 Cast resin for optical use NOF CORP (JP) 1996-05-08 EP disclosed
US-5336743-A Diallylphthalate component and an alkylene bis-allylcarbonate component NOF CORPORATION (JP) 1994-08-09 US disclosed
EP-0540003-A1 Cast resin for optical use NOF CORPORATION (JP) 1993-05-05 EP disclosed