Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30565097 | 1.00 | AKR1B1 (0.61) | AKR1B1TDP1ALDH1A1PTGS2BCAT2 | |
| SCHEMBL29674787 | 1.00 | AKR1B1 (0.61) | AKR1B1TDP1ALDH1A1PTGS2BCAT2 | |
| Hydrochloric Acid SCHEMBL2532034 | 0.98 | AKR1B1 (0.59) | AKR1B1TDP1ALDH1A1PTGS2BCAT2 | |
| Methylene Chloride SCHEMBL28048399 | 0.94 | AKR1B1 (0.55) | AKR1B1TDP1ALDH1A1PTGS2BCAT2 | |
| SCHEMBL1449282 | 0.84 | CA12 (0.47) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL1778391 | 0.84 | CA12 (0.47) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL30359 | 0.83 | AKR1B1 (0.76) | AKR1B1TDP1PTGS2BCAT2CXCL8 | |
| SCHEMBL29410826 | 0.83 | AKR1B1 (0.76) | AKR1B1TDP1PTGS2BCAT2CXCL8 | |
| SCHEMBL9064608 | 0.83 | ALDH1A1 (0.45) | AKR1B1ALDH1A1CA12CA1CA2 | |
| SCHEMBL9064385 | 0.83 | ALDH1A1 (0.45) | AKR1B1ALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1480 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371356-B | Nuciferine derivative, and preparation method and application thereof | 云南中医药大学 | 2026-05-19 | — | — | CN | claimed |
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| US-20250197356-A1 | METHOD FOR SYNTHESIZING NUCIFERINE OR DERIVATIVE THEREOF, DERIVATIVE OF NUCIFERINE AND USE THEREOF | HUAQIAO UNIVERSITY (CN) | 2025-06-19 | — | — | US | claimed |
| US-12291531-B2 | Matrine α-ketoamine compounds, preparation method therefor and use thereof | SHANGHAI XINGYE PHARMACEUTICAL TECHNOLOGY CO., LTD (CN) | 2025-05-06 | — | — | US | claimed |
| CN-115108905-B | Method for producing (Z) -trifluoromethaneenol ester by copper-catalyzed regioselective olefination and trifluoromethylation of carboxylic acid | 湖南大学 | 2025-04-08 | — | — | CN | claimed |
| CN-119751768-A | Functionalized polyolefin-based nanoparticle as well as preparation method and application thereof | 复旦大学 | 2025-04-04 | — | — | CN | claimed |
| CN-119371356-A | Nuciferine derivative, and preparation method and application thereof | 云南中医药大学 | 2025-01-28 | — | — | CN | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| CN-117903046-A | Preparation method of anti-epileptic drug pirenzenenaphthalene | 威海海洋职业学院 | 2024-04-19 | — | — | CN | claimed |
| CN-117756834-A | Synthesis method of 2- (aminocarbonylmethyl) phenylboronic acid pinacol ester | 大连双硼医药化工有限公司 | 2024-03-26 | — | — | CN | claimed |
| US-6403646-B1 | ADMINISTERING PHENYLBUTYRIC ACID OR DERIVATIVES TO TREAT LIVER DISEASE AND EMPHYSEMA CAUSED BY PROTEASE INHIBITOR TYPE Z MUTATION; STIMULATES SECRETION WITHOUT INCREASING SYNTHESIS OF PROTEIN | PERLMUTTER DAVID H (US) | 2002-06-11 | — | — | US | claimed |
| EP-0710648-B1 | Method for producing oxyindoles | KI CHEMICAL INDUSTRY CO LTD (JP) | 2002-04-03 | — | — | EP | claimed |
| EP-1124417-A2 | COMPOSITIONS COMPRISING PLANT CELL GROWTH REGULATING COMPOUNDS AND METHODS OF USE THEREOF | INVITROGEN CORPORATION (US) | 2001-08-22 | — | — | EP | claimed |
| WO-2000024249-A2 | COMPOSITIONS COMPRISING PLANT CELL GROWTH REGULATING COMPOUNDS AND METHODS OF USE THEREOF | INVITROGEN CORPORATION (US) | 2000-05-04 | — | — | WO | claimed |
| US-5679799-A | Method for producing oxyindoles | K-I CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-10-21 | — | — | US | claimed |
| EP-0710648-A1 | Method for producing oxyindoles | K I CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-05-08 | — | — | EP | claimed |
| EP-0134986-B1 | BIOLOGICALLY ACTIVE HEPTAPEPTIDES, AGENTS THEREOF AND THEIR USE | FARMITALIA CARLO ERBA S.r.l. (IT) | 1989-12-27 | — | — | EP | claimed |
| EP-0134986-A2 | Biologically active heptapeptides, agents thereof and their use | FARMITALIA CARLO ERBA S.r.l. (IT) | 1985-03-27 | — | — | EP | claimed |
| US-4307034-A | ALKYLATION | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-12-22 | — | — | US | claimed |
| US-3941814-A | Process for obtaining D(-)-and L(+)-α-azidophenylacetic acid | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1976-03-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250197356-A1 | METHOD FOR SYNTHESIZING NUCIFERINE OR DERIVATIVE THEREOF, DERIVATIVE OF NUCIFERINE AND USE THEREOF | NUCB2, NISCH, CYP46A1 | AKR1B1 439/4885TDP1 4451/4885ALDH1A1 894/4885 |
| US-12291531-B2 | Matrine α-ketoamine compounds, preparation method therefor and use thereof | TNF, KLKB1, KMO | AKR1B1 217/4885TDP1 1537/4885ALDH1A1 2902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.