Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 3/20 | 0.45 |
| ▸ | FABP3 | P05413 | 2/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3079552 | 0.87 | GABRA1 (0.52) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL11449736 | 0.84 | LMNA (0.44) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL24191005 | 0.79 | GABRA1 (0.34) | GABRA1GABRB2LMNATRPA1PTGS1 | |
| SCHEMBL25767282 | 0.79 | GABRA1 (0.31) | GABRA1GABRB2 | |
| SCHEMBL25767281 | 0.79 | GABRA1 (0.31) | GABRA1GABRB2 | |
| SCHEMBL19121112 | 0.78 | GABRA1 (0.33) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL28503898 | 0.77 | LMNA (0.50) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL1229146 | 0.77 | LMNA (0.38) | GABRA1GABRB2LMNATRPA1ALDH1A1 | |
| SCHEMBL6943696 | 0.76 | GABRA1 (0.65) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL20285914 | 0.76 | GABRA1 (0.43) | GABRA1GABRB2FABP4FABP3FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174689-A1 | SUBSTITUTED INDOLE MCL-1 INHIBITORS | VANDERBILT UNIVERSITY | 2017-06-22 | — | — | US | disclosed |
| EP-0564979-B1 | Method for the production of dixylylpropane | HOECHST AG (DE) | 1996-08-28 | — | — | EP | disclosed |
| US-5300717-A | Reacting o-xylene with propene; Friedel-Crafts catalyst; dehydrogenation. chlorination, condensation; intermediate for bisanhydride precursor for polyimides | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| EP-0564979-A2 | Method for the production of dixylylpropane | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174689-A1 | SUBSTITUTED INDOLE MCL-1 INHIBITORS | MCL1, BCL2L1, BCL3 | GABRA1 3538/4885GABRB2 2596/4885FABP4 3287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.