Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 7/20 | 0.62 |
| ▸ | PTGER4 | P35408 | 7/20 | 0.62 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.62 |
| ▸ | PTGER2 | P43116 | 7/20 | 0.62 |
| ▸ | HTR1A | P08908 | 3/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318261 | 0.86 | PTGER1 (0.52) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8675205 | 0.79 | PTGER1 (0.71) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8319420 | 0.76 | PTGER1 (1.00) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL9057460 | 0.76 | HTR1A (0.79) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8676795 | 0.76 | PTGER1 (0.63) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8675521 | 0.76 | PTGER1 (0.67) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL17197391 | 0.76 | HTR1A (0.79) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8677422 | 0.75 | PTGER1 (0.65) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8677351 | 0.74 | PTGER1 (0.64) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8318952 | 0.74 | PTGER1 (0.76) | PTGER1PTGER4PTGER3PTGER2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733033-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-09-25 | — | — | EP | disclosed |