SCHEMBL906474

SCHEMBL906474

O=C(OC12CC3CC(CC(C3)C1)C2)C(F)=C(F)F

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.38
NAAA Q02083 1/20 0.36
NPSR1 Q6W5P4 3/20 0.36
TSHR P16473 1/20 0.36
CYP17A1 P05093 3/20 0.35
EPHX2 P34913 2/20 0.35
EPHX1 P07099 2/20 0.33
CA2 P00918 1/20 0.33
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
GLA P06280 1/20 0.31
THRB P10828 1/20 0.31
CYP2C9 P11712 1/20 0.31
GAA P10253 1/20 0.30
SCN1A P35498 1/20 0.30
SCN2A Q99250 1/20 0.30
SCN3A Q9NY46 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27736443 0.83 CYP19A1 (0.44) CYP19A1NAAANPSR1TSHRCYP17A1
SCHEMBL22769989 0.80 CYP19A1 (0.38) CYP19A1NAAANPSR1TSHRCYP17A1
SCHEMBL2517522 0.79 CYP19A1 (0.42) CYP19A1NAAANPSR1TSHRCYP17A1
SCHEMBL7928678 0.77 CYP19A1 (0.41) CYP19A1NAAANPSR1TSHRCYP17A1
SCHEMBL7183809 0.77 CYP19A1 (0.41) CYP19A1NAAANPSR1TSHRCYP17A1
SCHEMBL18395311 0.75 CYP19A1 (0.40) CYP19A1NAAANPSR1TSHRCYP17A1
SCHEMBL27571638 0.75 CYP19A1 (0.40) CYP19A1NAAANPSR1TSHRCYP17A1
SCHEMBL16369107 0.75 CYP19A1 (0.40) CYP19A1NAAANPSR1TSHRCYP17A1
SCHEMBL8395205 0.75 NAAA (0.45) CYP19A1NAAANPSR1TSHRCYP17A1
SCHEMBL11016773 0.74 CYP19A1 (0.37) CYP19A1NAAANPSR1TSHRCYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2468780-B1 Copolymer and top coating composition JSR CORP (JP) 2013-11-13 EP disclosed
US-8580482-B2 Copolymer and top coating composition JSR CORPORATION (JP) 2013-11-12 US disclosed
EP-1806370-B1 COPOLYMER AND UPPER FILM-FORMING COMPOSITION JSR CORP (JP) 2013-05-22 EP disclosed
EP-2277929-B1 Copolymer and top coating composition JSR CORP (JP) 2012-11-21 EP disclosed
EP-2468780-A1 Copolymer and top coating composition JSR Corporation (JP) 2012-06-27 EP disclosed
US-20120101205-A1 COPOLYMER AND TOP COATING COMPOSITION JSR CORPORATION (JP) 2012-04-26 US disclosed
EP-2277929-A1 Copolymer and top coating composition JSR Corporation (JP) 2011-01-26 EP disclosed
US-20100266953-A1 COPOLYMER AND TOP COATING COMPOSITION JSR CORPORATION (JP) 2010-10-21 US disclosed
US-7781142-B2 Copolymer and top coating composition JSR CORPORATION (JP) 2010-08-24 US disclosed
US-20080038661-A1 Copolymer and Top Coating Composition JSR CORPORATION (JP) 2008-02-14 US disclosed
EP-1806370-A1 COPOLYMER AND UPPER FILM-FORMING COMPOSITION JSR Corporation (JP) 2007-07-11 EP disclosed
US-6730451-B2 FLUOROACRYLATE POLYMERS; TRANSPARENCY; PREVENTING NEGATIVE WORKING; LOW ABSORPTION OF FLUORINE EXCIMER LASER LIGHT; HIGH TRANSMITTANCE TO VACUUM ULTRAVIOLET RADITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-05-04 US disclosed
US-20010010890-A1 Polymers, chemical amplification resist compositions and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2001-08-02 US disclosed