Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | PGA5 | P0DJD9 | 1/20 | 0.47 |
| ▸ | CTSE | P14091 | 1/20 | 0.47 |
| ▸ | PGC | P20142 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266771 | 1.00 | REN (0.54) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7268089 | 0.93 | REN (0.62) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7268447 | 0.88 | REN (0.54) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7276336 | 0.87 | REN (0.60) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7275465 | 0.86 | REN (0.52) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7267995 | 0.86 | REN (0.52) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7267114 | 0.85 | REN (0.56) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7273905 | 0.85 | REN (0.49) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7267769 | 0.85 | REN (0.57) | REN | |
| SCHEMBL7268582 | 0.84 | REN (0.48) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5481036-A | RENIN INHIBITORS, HYPOTENSIVE AGENTS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-01-02 | — | — | US | disclosed |