Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NISCH | Q9Y2I1 | 11/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807038 | 0.79 | SMN1; SMN2 (0.56) | TSHRSMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL9246331 | 0.78 | NISCH (0.54) | SMN1; SMN2NISCHKDM4ECYP1A2ALDH1A1 | |
| SCHEMBL9868117 | 0.77 | NISCH (0.55) | NISCHKDM4ECYP1A2ALDH1A1CYP2D6 | |
| SCHEMBL6824337 | 0.75 | NISCH (0.56) | NISCHKDM4ECYP1A2ALDH1A1CYP2D6 | |
| SCHEMBL3912410 | 0.75 | PDE10A (0.56) | TSHRSMN1; SMN2KDM4EALDH1A1LMNA | |
| Pyromellitic Acid SCHEMBL216326 | 0.74 | NISCH (0.71) | TSHRNISCHCYP1A2ALDH1A1LMNA | |
| SCHEMBL8936695 | 0.73 | NISCH (0.41) | NISCHLMNAMAOAMAOB | |
| SCHEMBL27546361 | 0.73 | TSHR (0.64) | TSHRSMN1; SMN2KDM4EALDH1A1ADRA2A | |
| SCHEMBL5458072 | 0.73 | DHODH (0.54) | TSHRSMN1; SMN2KDM4ECYP1A2ALDH1A1 | |
| SCHEMBL1836133 | 0.73 | KDM4E (0.61) | TSHRSMN1; SMN2NISCHKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3024045-A | — | — | None | — | — | JP | disclosed |
| EP-0548560-B1 | Process for the manufacturing of halomaleic and halofumaric esters | AMERICAN CYANAMID CO (US) | 1996-01-10 | — | — | EP | disclosed |
| US-5478795-A | Selective postemergence control of undesirable plant species in the presence of crops | AMERICAN CYANAMID COMPANY (US) | 1995-12-26 | — | — | US | disclosed |
| EP-0402561-B1 | Process for the manufacture of anilinofumarate via chloromaleate or chlorofumarate or mixtures thereof | AMERICAN CYANAMID CO (US) | 1994-10-05 | — | — | EP | disclosed |
| EP-0548560-A2 | Process for the manufacturing of halomaleic and halofumaric esters | AMERICAN CYANAMID COMPANY (US) | 1993-06-30 | — | — | EP | disclosed |
| US-5214198-A | Dehydrohalogenation, phase tranfer catalyst | AMERICAN CYANAMID COMPANY (US) | 1993-05-25 | — | — | US | disclosed |
| US-5030271-A | Isopropylammonium 2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)nicotinate and 5-ethyl-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)nicotinic acid | AMERICAN CYANAMID COMPANY (US) | 1991-07-09 | — | — | US | disclosed |
| US-5030271-A | Isopropylammonium 2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)nicotinate and 5-ethyl-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)nicotinic acid | AMERICAN CYANAMID COMPANY (US) | 1991-07-09 | — | — | US | disclosed |
| US-5001254-A | Novel method for the preparation of quinoline-2,3-dicarboxylic | AMERICAN CYANAMID COMPANY | 1991-03-19 | — | — | US | disclosed |
| US-4996350-A | Solvent-free chlorination of dialkyl maleate; herbicide intermediates | AMERICAN CYANAMID COMPANY (US) | 1991-02-26 | — | — | US | disclosed |
| EP-0262305-A1 | Method for the preparation of anilinofumarate and quinoline-2,3-dicarboxylic acid | AMERICAN CYANAMID COMPANY (US) | 1988-04-06 | — | — | EP | disclosed |
| EP-0257433-A2 | Method for the preparation of quinoline-2,3-dicarboxylic acid | AMERICAN CYANAMID COMPANY (US) | 1988-03-02 | — | — | EP | disclosed |
| US-4719303-A | Preparation of substituted and unsubstituted 2-[(1-carbamoyl-1,2-dimethylpropyl)-carbamoyl]-3-quinolinecarboxylic, nicotinic and benzoic acids | AMERICAN CYANAMID COMPANY (US) | 1988-01-12 | — | — | US | disclosed |
| EP-0142718-B1 | PREPARATION OF SUBSTITUTED AND UNSUBSTITUTED 2-((1-CARBAMOYL-1,2-DIMETHYLPROPYL)-CARBAMOYL)-3-QUINOLINECARBOXYLIC, NICOTINIC AND BENZOIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1987-03-11 | — | — | EP | disclosed |
| US-4638068-A | 2-(2-imidazolin-2-yl)-pyridines and quinolines, process and intermediates for the preparation thereof, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1987-01-20 | — | — | US | disclosed |
| EP-0041623-B1 | SUBSTITUTED IMIDAZOLINYL NICOTINE ACIDS, ESTERS AND SALTS AND USE THEREOF AS HERBICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |
| EP-0142718-A1 | Preparation of substituted and unsubstituted 2-((1-carbamoyl-1,2-dimethylpropyl)-carbamoyl)-3-quinolinecarboxylic, nicotinic and benzoic acids | AMERICAN CYANAMID COMPANY (US) | 1985-05-29 | — | — | EP | disclosed |
| EP-0041624-B1 | METHOD TO BENEFICIALLY INFLUENCE & ALTER THE DEVELOPMENT & LIFE CYCLE OF AGRONOMIC AND HORTICULTURAL CROPS WITH CERTAIN IMIDAZOLINYL NICOTINIC ACIDS AND DERIVATIVES THEREOF | AMERICAN CYANAMID COMPANY (US) | 1984-02-01 | — | — | EP | disclosed |
| EP-0041623-A2 | Substituted imidazolinyl nicotine acids, esters and salts and use thereof as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1981-12-16 | — | — | EP | disclosed |
| EP-0041624-A2 | Method to beneficially influence & alter the development & life cycle of agronomic and horticultural crops with certain imidazolinyl nicotinic acids and derivatives thereof | AMERICAN CYANAMID COMPANY (US) | 1981-12-16 | — | — | EP | disclosed |