Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 7/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.30 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064807 | 1.00 | THRB (0.39) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL9064787 | 1.00 | THRB (0.39) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL19356729 | 0.94 | LMNA (0.41) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL19356621 | 0.94 | LMNA (0.41) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL11445880 | 0.94 | LMNA (0.41) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL18037827 | 0.94 | LMNA (0.41) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL3490323 | 0.94 | LMNA (0.41) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL19356795 | 0.94 | LMNA (0.41) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL19356754 | 0.94 | LMNA (0.41) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL19356625 | 0.94 | LMNA (0.41) | THRBMEN1HTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552476-A | LUBRICANTS OR WATERPROOFING FOR SILICA, CELLULOSE OR PROTEIN SURFACES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-03 | — | — | US | claimed |
| US-5552476-A | LUBRICANTS OR WATERPROOFING FOR SILICA, CELLULOSE OR PROTEIN SURFACES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-03 | — | — | US | disclosed |