Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517596 | 0.76 | MME (0.33) | MEN1KMT2AMMESMN1; SMN2TAS1R3 | |
| SCHEMBL11652425 | 0.75 | SMN1; SMN2 (0.46) | KMT2AMMECA1CA2SMN1; SMN2 | |
| SCHEMBL9065165 | 0.72 | TSHR (0.36) | MEN1KMT2ASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL3687345 | 0.72 | SMN1; SMN2 (0.39) | KMT2AMMECA1CA2SMN1; SMN2 | |
| SCHEMBL28306501 | 0.72 | — | — | |
| SCHEMBL452544 | 0.70 | ALDH1A1 (0.41) | MEN1KMT2AMMECA1CA2 | |
| SCHEMBL26295440 | 0.69 | ALDH1A1 (0.38) | MEN1KMT2AMMECA1CA2 | |
| SCHEMBL1059738 | 0.69 | MME (0.56) | MMESMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL28391905 | 0.68 | CA1 (0.32) | CA1CA2 | |
| SCHEMBL9180783 | 0.67 | MGAM (0.36) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569780-A | Dialkyl 2-haloethyl malonates | HULS AKTIENGESELLSCHAFT (DE) | 1996-10-29 | — | — | US | disclosed |
| US-5463111-A | Process for preparing dialkyl 2-haloethyl malonates | HULS AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0507930-B1 | MEASUREMENT OF COLOR REACTIONS BY MONITORING A CHANGE OF FLUORESCENCE | BAXTER DIAGNOSTICS INC (US) | 1995-06-21 | — | — | EP | disclosed |
| US-5173434-A | Sandwiching a solution containing substance to be measured and chromogenic agent between a light source and an isolated fluorophore embedded in an inert light transmissive matrix and detecting change in flourophore emission | BAXTER DIAGNOSTICS INC. (US) | 1992-12-22 | — | — | US | disclosed |