Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9180783 | 0.75 | MGAM (0.36) | TSHR | |
| SCHEMBL11428981 | 0.75 | — | — | |
| SCHEMBL15515336 | 0.74 | TSHR (0.45) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL452543 | 0.73 | TDP1 (0.43) | TSHRMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9065166 | 0.72 | MEN1 (0.33) | TSHRMEN1KMT2ASMN1; SMN2TAS1R3 | |
| SCHEMBL275280 | 0.71 | SMN1; SMN2 (0.52) | TSHRKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9180785 | 0.70 | ALOX15 (0.31) | TSHRMEN1KMT2A | |
| SCHEMBL28812072 | 0.70 | SMN1; SMN2 (0.39) | TSHRMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10805452 | 0.68 | SMN1; SMN2 (0.50) | TSHRKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL26658220 | 0.68 | SMN1; SMN2 (0.50) | TSHRKMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569780-A | Dialkyl 2-haloethyl malonates | HULS AKTIENGESELLSCHAFT (DE) | 1996-10-29 | — | — | US | disclosed |