SCHEMBL9065190

SCHEMBL9065190

CC(C)(C)c1cccc(-c2c3c(c(-c4cccc(C(C)(C)C)c4C(C)(C)C)c(-c4cccc(C(C)(C)C)c4C(C)(C)C)c2-c2cccc(C(C)(C)C)c2C(C)(C)C)-c2ccccc2-3)c1C(C)(C)C.OP(O)O

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.42
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
PTPN5 P54829 1/20 0.35
NPSR1 Q6W5P4 1/20 0.33
KIF11 P52732 1/20 0.33
ALOX12 P18054 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD11B1 P28845 1/20 0.31
PDK2 Q15119 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL499865 0.92 CA2 (0.43) CA2ALDH1A1TSHRTDP1GABRA1
SCHEMBL9065196 0.89 CA2 (0.36) CA2ALDH1A1TSHRTDP1GABRA1
SCHEMBL29392891 0.83 CA2 (0.37) CA2ALDH1A1TSHRTDP1GABRA1
SCHEMBL1904817 0.82 CA2 (0.35) CA2ALDH1A1TSHRTDP1GABRA1
SCHEMBL27524063 0.81 CA2 (0.40) CA2ALDH1A1TSHRTDP1GABRA1
SCHEMBL2906636 0.80 CA2 (0.35) CA2ALDH1A1TSHRTDP1GABRA1
SCHEMBL31658324 0.80 CA2 (0.35) CA2ALDH1A1TSHRTDP1GABRA1
SCHEMBL499866 0.80 CA2 (0.36) CA2ALDH1A1TSHRTDP1GABRA1
SCHEMBL4461655 0.80 CA2 (0.50) CA2ALDH1A1TSHRTDP1GABRA1
SCHEMBL2958450 0.77 CA2 (0.33) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5589541-A EXTRUSION GRAFTING WITH STYRENE, PACKAGING MATERIAL DAINIPPON INK AND CHEMICALS INC. (JP) 1996-12-31 US disclosed