SCHEMBL9065196

SCHEMBL9065196

CC(C)(C)c1cccc(-c2c(-c3cccc(C(C)(C)C)c3C(C)(C)C)c(-c3cccc(C(C)(C)C)c3C(C)(C)C)c3c(c2-c2cccc(C(C)(C)C)c2C(C)(C)C)=c2ccccc2=3)c1C(C)(C)C.OP(O)O

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.36
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
PTPN5 P54829 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL499866 0.94 CA2 (0.36) CA2ALDH1A1TSHRTDP1GABRA1
SCHEMBL9065190 0.89 CA2 (0.42) CA2ALDH1A1TSHRTDP1GABRA1
SCHEMBL499865 0.81 CA2 (0.43) CA2ALDH1A1TSHRTDP1GABRA1
SCHEMBL1904820 0.79 PTPN5 (0.31) CA2ALDH1A1TSHRTDP1PTPN5
SCHEMBL2051029 0.78 CA2 (0.42) CA2ALDH1A1TSHRTDP1GABRA1
SCHEMBL27524064 0.77 CA2 (0.36) CA2ALDH1A1TSHRTDP1GABRA1
SCHEMBL1884096 0.74
SCHEMBL253424 0.74 ALDH1A1 (0.39) ALDH1A1TSHRTDP1
SCHEMBL3329301 0.74 GABRA1 (0.32) ALDH1A1TSHRTDP1GABRA1GABRB2
SCHEMBL2906636 0.74 CA2 (0.35) CA2ALDH1A1TSHRTDP1GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5589541-A EXTRUSION GRAFTING WITH STYRENE, PACKAGING MATERIAL DAINIPPON INK AND CHEMICALS INC. (JP) 1996-12-31 US disclosed