Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | DTYMK | P23919 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6053554 | 0.81 | GRIK1 (0.48) | GRM4GRM8KMO | |
| SCHEMBL6053553 | 0.81 | GRIK1 (0.48) | GRM4GRM8KMO | |
| SCHEMBL9066405 | 0.78 | PRNP (0.42) | CASP6DTYMK | |
| SCHEMBL9064821 | 0.77 | GRM8 (0.49) | GRM4GRM8KMO | |
| SCHEMBL8610040 | 0.75 | KDM4E (0.52) | GRM4GRM8 | |
| SCHEMBL2003176 | 0.75 | KDM4E (0.52) | GRM4GRM8 | |
| SCHEMBL8904293 | 0.75 | KDM4E (0.52) | GRM4GRM8 | |
| SCHEMBL8963352 | 0.75 | MAPT (0.61) | GRM4GRM8KMO | |
| SCHEMBL8964242 | 0.75 | MAPT (0.61) | GRM4GRM8KMO | |
| SCHEMBL14508392 | 0.75 | DTYMK (0.66) | CASP6DTYMKGRM4GRM8KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516936-A | TREATMENT OF NEUROLOGICAL DISORDERS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1996-05-14 | — | — | US | claimed |
| EP-0581907-A4 | — | — | 1994-04-06 | — | — | EP | claimed |
| EP-0581907-A1 | INHIBITORS OF KYNURENINASE | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1994-02-09 | — | — | EP | claimed |
| WO-1992018003-A1 | INHIBITORS OF KYNURENINASE | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1992-10-29 | — | — | WO | claimed |
| US-5516936-A | TREATMENT OF NEUROLOGICAL DISORDERS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1996-05-14 | — | — | US | disclosed |
| EP-0581907-A4 | — | — | 1994-04-06 | — | — | EP | disclosed |
| EP-0581907-A1 | INHIBITORS OF KYNURENINASE | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1994-02-09 | — | — | EP | disclosed |
| WO-1992018003-A1 | INHIBITORS OF KYNURENINASE | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1992-10-29 | — | — | WO | disclosed |