Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.48 |
| ▸ | GRM8 | O00222 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | PTPRA | P18433 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6053553 | 1.00 | GRIK1 (0.48) | GRIK1GRIK2GRM8GRM6GRM4 | |
| SCHEMBL10817499 | 0.84 | MAPT (0.44) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL9065283 | 0.81 | CASP6 (0.44) | GRM8GRM4KMO | |
| SCHEMBL7079082 | 0.79 | MMP1 (0.47) | MAPTMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL7310938 | 0.79 | ACE (0.55) | GRIK1GRIK2GRM8GRM6GRM4 | |
| SCHEMBL5695662 | 0.79 | ACE (0.55) | GRIK1GRIK2GRM8GRM6GRM4 | |
| Cysteine SCHEMBL3614637 | 0.79 | PTGS1 (0.47) | GRIK1GRIK2GRM8GRM6GRM4 | |
| Cysteine SCHEMBL3614622 | 0.79 | PTGS1 (0.47) | GRIK1GRIK2GRM8GRM6GRM4 | |
| SCHEMBL8964242 | 0.79 | MAPT (0.61) | GRM8GRM4KMOPTPRAMAPT | |
| SCHEMBL8963352 | 0.79 | MAPT (0.61) | GRM8GRM4KMOPTPRAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006029389-A2 | TRYPTOPHAN-PROCESSING ENZYMES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM | DIVERSA CORPORATION (US) | 2006-03-16 | — | — | WO | disclosed |