SCHEMBL9065289

SCHEMBL9065289

CCCC(=O)OC(CC)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
LMNA P02545 5/20 0.41
HDAC1 Q13547 2/20 0.39
HDAC2 Q92769 2/20 0.39
FFAR3 O14843 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
ACE P12821 1/20 0.39
MAPK1 P28482 3/20 0.37
MAPT P10636 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
CHRM1 P11229 1/20 0.34
AKR1A1 P14550 1/20 0.34
CHRM3 P20309 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
ADRA1A P35348 1/20 0.34
HRH1 P35367 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29176812 0.98 ALDH1A1 (0.44) ALDH1A1LMNAHDAC1HDAC2FFAR3
SCHEMBL8997372 0.84 LMNA (0.61) ALDH1A1LMNAMAPK1MAPTCYP1A2
SCHEMBL9215060 0.84 LMNA (0.61) ALDH1A1LMNAMAPK1MAPTCYP1A2
SCHEMBL180769 0.83 ALDH1A1 (0.46) ALDH1A1LMNAHDAC1HDAC2FFAR3
SCHEMBL28023347 0.82 SMN1; SMN2 (0.39) ALDH1A1HDAC1HDAC2FFAR3ACE
SCHEMBL9219486 0.82 CA1 (0.39) LMNAACESMN1; SMN2CYP1A2BLM
SCHEMBL4952099 0.82 ALDH1A1 (0.41) ALDH1A1LMNAHDAC1HDAC2FFAR3
SCHEMBL28380784 0.82 LMNA (0.44) ALDH1A1LMNAMAPK1MAPTTDP1
SCHEMBL1404146 0.80 KLK7 (0.38) HDAC1HDAC2ACEMAPK1SMN1; SMN2
SCHEMBL27521149 0.79 ALDH1A1 (0.43) ALDH1A1LMNAMAPK1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113474324-A Isobutyrate compounds having n-butyryloxy group at alpha position, fragrance compositions and use as fragrance 三菱瓦斯化学株式会社 2021-10-01 CN disclosed
US-5510428-A Compositions, epoxized compositions, a heat curable resin composition, an epoxy resin composition, radically polymerized compositions, a curable resin composition and a polymer having epoxy groups DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1996-04-23 US disclosed
WO-1995009145-A1 NUTRITIVE GLYCEROL ESTERS OF β-ACYLOXY BUTYRATES EASTMAN CHEMICAL COMPANY (US) 1995-04-06 WO disclosed
EP-0141968-B1 PYRROLYLAMINOPIPERIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1988-05-18 EP disclosed
EP-0266217-A2 Process for producing optically active compounds CHISSO CORPORATION (JP) 1988-05-04 EP disclosed
US-4546105-A ANALGESICS HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1985-10-08 US disclosed
EP-0141968-A1 Pyrrolylaminopiperidines, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1985-05-22 EP disclosed
US-4452803-A ANALGESICS HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1984-06-05 US disclosed