Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30271358 | 0.85 | MAPK8 (0.49) | MAPK8L3MBTL1DRD4BTKCDK9 | |
| SCHEMBL1671304 | 0.85 | MAPK8 (0.49) | MAPK8L3MBTL1DRD4BTKCDK9 | |
| SCHEMBL30436204 | 0.80 | DRD4 (0.35) | L3MBTL1DRD4CDK9DYRK1ADYRK2 | |
| SCHEMBL12483137 | 0.80 | DRD4 (0.35) | L3MBTL1DRD4CDK9DYRK1ADYRK2 | |
| SCHEMBL10910803 | 0.78 | MCHR1 (0.42) | MAPK8L3MBTL1DRD4CDK9DYRK1A | |
| SCHEMBL10911295 | 0.76 | MCHR1 (0.44) | L3MBTL1CDK9DYRK1ADYRK2ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL2186005 | 0.76 | MCHR1 (0.41) | MAPK8L3MBTL1DRD4CDK9DYRK1A | |
| SCHEMBL27852278 | 0.75 | MCHR1 (0.45) | CDK9DYRK1ADYRK2TSHRKCNH2 | |
| SCHEMBL7520131 | 0.74 | MCHR1 (0.47) | CDK9DYRK1ADYRK2TSHRKCNH2 | |
| SCHEMBL27852180 | 0.74 | MCHR1 (0.47) | CDK9DYRK1ADYRK2TSHRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486615-A | Method of making asymmetric DE ring intermediates for the synthesis of camptothecin analogs | NORTH CAROLINA STATE UNIVERSITY (US) | 1996-01-23 | — | — | US | disclosed |
| US-5395939-A | Method of making asymmetric de ring intermediates for the synthesis of camptothecin and camptothecin analogs | NORTH CAROLINA STATE UNIVERSITY (US) | 1995-03-07 | — | — | US | disclosed |