SCHEMBL9065615

SCHEMBL9065615

CC(C)OCCC(=O)Nc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.61
CYP3A4 P08684 2/20 0.61
CYP2C9 P11712 2/20 0.61
CYP2C19 P33261 2/20 0.61
HDAC3 O15379 4/20 0.55
HDAC4 P56524 4/20 0.55
HDAC1 Q13547 4/20 0.55
HDAC7 Q8WUI4 4/20 0.55
HDAC2 Q92769 4/20 0.55
HDAC10 Q969S8 4/20 0.55
HDAC11 Q96DB2 4/20 0.55
HDAC8 Q9BY41 4/20 0.55
HDAC6 Q9UBN7 4/20 0.55
HDAC9 Q9UKV0 4/20 0.55
HDAC5 Q9UQL6 4/20 0.55
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
KMT2A Q03164 2/20 0.54
TP53 P04637 1/20 0.54
MAPT P10636 5/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9911434 0.83 HPGD (0.58) CYP1A2CYP2C19HDAC3HDAC4HDAC1
SCHEMBL3469024 0.81 CYP3A4 (0.67) CYP1A2CYP3A4CYP2C9CYP2C19HDAC3
SCHEMBL12459476 0.79 NPC1 (0.62) NPC1RAB9AKMT2ATP53L3MBTL1
SCHEMBL11202781 0.78 CYP1A2 (0.55) CYP1A2CYP3A4CYP2C9CYP2C19HDAC3
SCHEMBL8171777 0.78 NAMPT (0.64) CYP1A2CYP3A4CYP2C9CYP2C19HDAC3
SCHEMBL9223090 0.78 CYP3A4 (0.63) CYP1A2CYP3A4CYP2C9CYP2C19HDAC3
SCHEMBL3342586 0.78 L3MBTL1 (0.80) CYP1A2CYP3A4CYP2C9CYP2C19HDAC3
SCHEMBL14133123 0.78 EPHX1 (0.55) HDAC1HDAC8HDAC6MAPTL3MBTL1
SCHEMBL1259422 0.77 HDAC3 (0.63) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL11420601 0.77 MAPT (0.61) CYP1A2CYP3A4CYP2C9CYP2C19HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996015667-A2 ANTIDOTE COMPOSITION AND METHOD FOR USE OF THE COMPOSITION Nitrokémia Rt. (HU) 1996-05-30 WO disclosed
CN-87102879-A Benzhydryl compounds as herbicide antidotes 1987-10-28 CN disclosed
EP-0064353-A1 Use of 2,4-disubstituted-5-thiazolecarboxylic acids and derivatives for reducing injury to crop plants by acetamide herbicides MONSANTO COMPANY (US) 1982-11-10 EP disclosed