Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.80 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.69 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.69 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.69 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.69 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.69 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | BRD4 | O60885 | 1/20 | 0.68 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.68 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94252 | 0.93 | L3MBTL1 (0.89) | L3MBTL1MAPTHTTSMN1; SMN2HDAC4 | |
| SCHEMBL12112926 | 0.91 | MAPT (0.79) | L3MBTL1MAPTHTTSMN1; SMN2HDAC4 | |
| SCHEMBL517309 | 0.91 | HDAC4 (0.81) | HDAC4HDAC1HDAC7HDAC11HDAC8 | |
| SCHEMBL6296181 | 0.91 | HDAC4 (0.75) | L3MBTL1MAPTHTTHDAC4HDAC1 | |
| SCHEMBL13010739 | 0.89 | L3MBTL1 (0.67) | L3MBTL1MAPTHTTSMN1; SMN2HDAC4 | |
| SCHEMBL14966662 | 0.89 | L3MBTL1 (1.00) | L3MBTL1MAPTHTTSMN1; SMN2HDAC4 | |
| SCHEMBL8974891 | 0.89 | L3MBTL1 (0.67) | L3MBTL1MAPTHTTSMN1; SMN2HDAC4 | |
| SCHEMBL22786946 | 0.89 | L3MBTL1 (0.67) | L3MBTL1MAPTHTTSMN1; SMN2HDAC4 | |
| Benzophenone SCHEMBL8650084 | 0.89 | ALDH1A1 (0.68) | L3MBTL1MAPTHTTSMN1; SMN2HDAC4 | |
| SCHEMBL3353284 | 0.89 | L3MBTL1 (0.72) | L3MBTL1MAPTHTTSMN1; SMN2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453789-A2 | N,N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | Elan Pharmaceuticals, Inc. (US) | 2004-09-08 | — | — | EP | claimed |
| WO-2003040096-A2 | N, N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | ELAN PHARMACEUTICALS, INC. (US) | 2003-05-15 | — | — | WO | claimed |
| WO-2019005563-A1 | METHODS RELATED TO ACTIVATION OF THE BONE MORPHOGENIC PROTEIN SIGNALING PATHWAY | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2019-01-03 | — | — | WO | disclosed |
| US-20170189277-A1 | COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF | L'OREAL (FR) | 2017-07-06 | — | — | US | disclosed |
| US-20150190320-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE SUNSCREEN PARTICLES | L'OREAL (FR) | 2015-07-09 | — | — | US | disclosed |
| US-20150157539-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE PARTICLES | L'OREAL (FR) | 2015-06-11 | — | — | US | disclosed |
| US-8882902-B2 | Composite pigment and method for preparation thereof | L'OREAL (FR) | 2014-11-11 | — | — | US | disclosed |
| US-20130309285-A1 | COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF | L'OREAL (FR) | 2013-11-21 | — | — | US | disclosed |
| US-20130259912-A1 | COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF | L'OREAL (FR) | 2013-10-03 | — | — | US | disclosed |
| CN-102985494-A | Dye compositions and dye synthesis | GE HEALTHCARE AS | 2013-03-20 | — | — | CN | disclosed |
| US-20100162416-A1 | Multi-stage stem cell carcinogenesis | STEMLIFELINE, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| EP-0468648-B1 | Anionic bis(hydroxynaphthylamino) disazo dyestuffs and use thereof for ink jet printing | ZENECA LTD (GB) | 1995-09-20 | — | — | EP | disclosed |
| US-5262527-A | Disazo dyes suitable for use in ink jet printing | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-11-16 | — | — | US | disclosed |
| EP-0557721-A2 | Crystalline polypropylene resin composition and amide compounds | NEW JAPAN CHEMICAL CO.,LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |
| EP-0155194-B2 | THERMOPLASTIC RESIN COMPOSITIONS HAVING IMPROVED MOLDABILITY | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1993-07-07 | — | — | EP | disclosed |
| US-5106919-A | Acrylic polymers of acids or esters imidized by an N-aryl amide, sulfonamide or urea; high glass transition temperatures | MOUNTEDIPE S.R.L. (IT) | 1992-04-21 | — | — | US | disclosed |
| EP-0382167-A1 | Process for preparation of compatible mixtures of N-aryl polyglutarimides with styrene copolymers | ENICHEM S.p.A. (IT) | 1990-08-16 | — | — | EP | disclosed |
| EP-0155194-B1 | THERMOPLASTIC RESIN COMPOSITIONS HAVING IMPROVED MOLDABILITY | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1989-06-07 | — | — | EP | disclosed |
| US-4684684-A | HEAT RESISTANCE | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1987-08-04 | — | — | US | disclosed |
| EP-0155194-A2 | Thermoplastic resin compositions having improved moldability | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1985-09-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170189277-A1 | COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF | TYR, RAB5IF, MITF | L3MBTL1 4529/4885MAPT 1171/4885HTT 410/4885 |
| US-20130259912-A1 | COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF | TYR, MITF, PUF60 | L3MBTL1 4482/4885MAPT 825/4885HTT 415/4885 |
| US-20150157539-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE PARTICLES | MITF, RAB5IF, TYR | L3MBTL1 4562/4885MAPT 922/4885HTT 652/4885 |
| US-20130309285-A1 | COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF | TYR, RAB5IF, MITF | L3MBTL1 4529/4885MAPT 1171/4885HTT 410/4885 |
| US-20150190320-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE SUNSCREEN PARTICLES | XPA, ERCC1, ERCC4 | L3MBTL1 4246/4885MAPT 2352/4885HTT 512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.