Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9066241 | 0.87 | ALDH1A1 (0.40) | CYP4F2CYP4A11HTTALDH1A1PKM | |
| SCHEMBL56546 | 0.87 | — | — | |
| Ammonia Solution, Strong SCHEMBL28110856 | 0.84 | ALDH1A1 (0.46) | CYP4F2CYP4A11HTTALDH1A1PKM | |
| Acetic Acid SCHEMBL28138458 | 0.80 | ALDH1A1 (0.46) | CYP4F2CYP4A11HTTALDH1A1PKM | |
| Trichloroacetic Acid SCHEMBL28680224 | 0.80 | ALDH1A1 (0.48) | CYP4F2CYP4A11HTTALDH1A1PKM | |
| Hexane SCHEMBL27932185 | 0.78 | MEN1 (0.49) | CYP4F2CYP4A11HTTALDH1A1PKM | |
| Bicarbonate SCHEMBL9390375 | 0.78 | ALDH1A1 (0.40) | CYP4F2CYP4A11HTTALDH1A1PKM | |
| Propene SCHEMBL9081847 | 0.75 | ALDH1A1 (0.37) | CYP4F2CYP4A11HTTALDH1A1PKM | |
| SCHEMBL3160237 | 0.72 | ALDH1A1 (0.48) | CYP4F2CYP4A11HTTALDH1A1PKM | |
| Ether SCHEMBL9254589 | 0.72 | CYP4F2 (0.41) | CYP4F2CYP4A11HTTALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712871-A1 | Process for the production of homogeneous ethylene propylene rubbers using a vanadium catalyst supported on magnesium chloride | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1996-05-22 | — | — | EP | claimed |