Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28559675 | 0.89 | ALDH1A1 (0.41) | TDP1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL29258067 | 0.87 | ALOX15 (0.43) | TDP1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL2224230 | 0.86 | TDP1 (0.54) | TDP1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL4613905 | 0.85 | TDP1 (0.50) | TDP1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL14580010 | 0.85 | TDP1 (0.53) | TDP1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL6080172 | 0.83 | TDP1 (0.51) | TDP1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL7641684 | 0.83 | TDP1 (0.51) | TDP1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL6080202 | 0.83 | TDP1 (0.51) | TDP1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL7659602 | 0.80 | TDP1 (0.56) | TDP1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL11655565 | 0.80 | TDP1 (0.56) | TDP1MEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113087710-A | Preparation method of ketorolac tromethamine intermediate | 鲁南制药集团股份有限公司 | 2021-07-09 | — | — | CN | claimed |
| CN-103764690-B | Process for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer | 东邦钛株式会社 | 2016-12-14 | — | — | CN | disclosed |
| CN-103764690-A | Process for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer | TOHO TITANIUM CO LTD | 2014-04-30 | — | — | CN | disclosed |
| US-5569780-A | Dialkyl 2-haloethyl malonates | HULS AKTIENGESELLSCHAFT (DE) | 1996-10-29 | — | — | US | disclosed |
| US-5463111-A | Process for preparing dialkyl 2-haloethyl malonates | HULS AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |