SCHEMBL9065737

SCHEMBL9065737

CCC(C)C1CCC(c2cc(Cl)c(O)c(Cl)c2)(c2cc(Cl)c(O)c(Cl)c2)CC1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.33
SLC6A4 P31645 5/20 0.31
SLC6A3 Q01959 5/20 0.31
SLC6A2 P23975 1/20 0.31
CYP2C9 P11712 2/20 0.31
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
CYP1A2 P05177 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
CYP2C19 P33261 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17636599 0.87 SHBG (0.37) ACHESLC6A4SLC6A3SLC6A2CYP2C9
SCHEMBL9066691 0.84 ACHE (0.36) ACHESLC6A4SLC6A3SLC6A2CYP2C9
SCHEMBL9065939 0.82 ACHE (0.33) ACHECYP2C9CYP2D6HSD17B10
SCHEMBL9066280 0.77 ESR2 (0.47) ACHESLC6A3SLC6A2CYP2C9CYP2D6
SCHEMBL9067006 0.76 ACHE (0.39) ACHESLC6A4SLC6A3CYP2C9CYP2D6
SCHEMBL9074164 0.73 KDM4E (0.36) ACHESLC6A4SLC6A3CYP2C9CYP2D6
SCHEMBL9073978 0.72 ACHE (0.36) ACHESLC6A4SLC6A3CYP2C9CYP2D6
SCHEMBL17636605 0.72 ACHE (0.36) ACHESLC6A4SLC6A3CYP2C9CYP2D6
SCHEMBL9074141 0.71 ACHE (0.36) ACHESLC6A4SLC6A3SLC6A2CYP2C9
SCHEMBL9066563 0.70 TSHR (0.41) ACHESLC6A4SLC6A3SLC6A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0469403-B1 High molecular weight polyester based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1996-02-28 EP disclosed
EP-0469404-B1 Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1996-02-28 EP disclosed
EP-0469404-A2 Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1992-02-05 EP disclosed
EP-0469403-A2 High molecular weight polyester based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1992-02-05 EP disclosed
US-5034457-A Polycarbonate for use in molding materials for laminated films and for electronics BAYER AKTIENGESELLSCHAFT (DE) 1991-07-23 US disclosed
US-5010162-A Polycarbonate of alkyl cyclohexylidene bisphenol BAYER AKTIENGESELLSCHAFT (DE) 1991-04-23 US disclosed
EP-0387593-A2 Thermoplastic alloys of polycarbonates based on substituted cyclohexylidenbisphenols BAYER AG (DE) 1990-09-19 EP disclosed
EP-0374656-A2 Polycarbonates from alkyl cyclohexylidene diphenols BAYER AG (DE) 1990-06-27 EP disclosed